DEFIBROTIDE for Thrombosis: Side Effects & Safety Data
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There are 7 adverse event reports in the FDA FAERS database where DEFIBROTIDE was used for Thrombosis.
Most Reported Side Effects for DEFIBROTIDE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 1,323 | 35.4% | 375 | 180 |
| Venoocclusive disease | 576 | 15.4% | 125 | 79 |
| Death | 463 | 12.4% | 463 | 148 |
| Multiple organ dysfunction syndrome | 372 | 10.0% | 337 | 125 |
| Venoocclusive liver disease | 355 | 9.5% | 272 | 73 |
| Intentional product use issue | 201 | 5.4% | 39 | 31 |
| Hypotension | 169 | 4.5% | 134 | 72 |
| Haemorrhage | 156 | 4.2% | 60 | 35 |
| Sepsis | 143 | 3.8% | 110 | 56 |
| Acute graft versus host disease | 140 | 3.7% | 69 | 56 |
| Gastrointestinal haemorrhage | 125 | 3.3% | 71 | 48 |
| Septic shock | 113 | 3.0% | 107 | 61 |
| Renal failure | 111 | 3.0% | 68 | 47 |
| Drug ineffective | 106 | 2.8% | 72 | 27 |
| Disease progression | 100 | 2.7% | 78 | 16 |
Other Indications for DEFIBROTIDE
Venoocclusive disease (1,325)
Venoocclusive liver disease (1,228)
Prophylaxis (1,073)
Product used for unknown indication (375)
Thrombotic microangiopathy (34)
Covid-19 (15)
Pulmonary veno-occlusive disease (8)
Hepatic failure (7)
Off label use (7)
Microangiopathy (6)
Other Drugs Used for Thrombosis
RIVAROXABAN (5,425)
APIXABAN (1,201)
WARFARIN (1,128)
ENOXAPARIN (849)
HEPARIN (378)
ASPIRIN (341)
CLOPIDOGREL BISULFATE (331)
SODIUM (238)
DABIGATRAN ETEXILATE (229)
DALTEPARIN (209)