Does DEFIBROTIDE Cause Febrile neutropenia? 54 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 54 reports of Febrile neutropenia have been filed in association with DEFIBROTIDE (DEFITELIO). This represents 1.4% of all adverse event reports for DEFIBROTIDE.
54
Reports of Febrile neutropenia with DEFIBROTIDE
1.4%
of all DEFIBROTIDE reports
7
Deaths
21
Hospitalizations
How Dangerous Is Febrile neutropenia From DEFIBROTIDE?
Of the 54 reports, 7 (13.0%) resulted in death, 21 (38.9%) required hospitalization, and 5 (9.3%) were considered life-threatening.
Is Febrile neutropenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEFIBROTIDE. However, 54 reports have been filed with the FAERS database.
What Other Side Effects Does DEFIBROTIDE Cause?
Off label use (1,323)
Venoocclusive disease (576)
Death (463)
Multiple organ dysfunction syndrome (372)
Venoocclusive liver disease (355)
Intentional product use issue (201)
Hypotension (169)
Haemorrhage (156)
Sepsis (143)
Acute graft versus host disease (140)
What Other Drugs Cause Febrile neutropenia?
CYCLOPHOSPHAMIDE (11,318)
DOXORUBICIN (8,844)
VINCRISTINE (8,676)
RITUXIMAB (6,382)
CYTARABINE (6,142)
METHOTREXATE (6,091)
ETOPOSIDE (5,966)
CARBOPLATIN (4,888)
DEXAMETHASONE (4,382)
PREDNISONE (3,956)
Which DEFIBROTIDE Alternatives Have Lower Febrile neutropenia Risk?
DEFIBROTIDE vs DEFLAZACORT
DEFIBROTIDE vs DEGARELIX
DEFIBROTIDE vs DELAFLOXACIN MEGLUMINE
DEFIBROTIDE vs DELAMANID
DEFIBROTIDE vs DELANDISTROGENE MOXEPARVOVEC-ROKL