Does DEFIBROTIDE Cause Pulmonary haemorrhage? 55 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 55 reports of Pulmonary haemorrhage have been filed in association with DEFIBROTIDE (DEFITELIO). This represents 1.5% of all adverse event reports for DEFIBROTIDE.
55
Reports of Pulmonary haemorrhage with DEFIBROTIDE
1.5%
of all DEFIBROTIDE reports
42
Deaths
20
Hospitalizations
How Dangerous Is Pulmonary haemorrhage From DEFIBROTIDE?
Of the 55 reports, 42 (76.4%) resulted in death, 20 (36.4%) required hospitalization, and 9 (16.4%) were considered life-threatening.
Is Pulmonary haemorrhage Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEFIBROTIDE. However, 55 reports have been filed with the FAERS database.
What Other Side Effects Does DEFIBROTIDE Cause?
Off label use (1,323)
Venoocclusive disease (576)
Death (463)
Multiple organ dysfunction syndrome (372)
Venoocclusive liver disease (355)
Intentional product use issue (201)
Hypotension (169)
Haemorrhage (156)
Sepsis (143)
Acute graft versus host disease (140)
What Other Drugs Cause Pulmonary haemorrhage?
RIVAROXABAN (322)
METHOTREXATE (226)
ASPIRIN (221)
CYCLOPHOSPHAMIDE (205)
DEXAMETHASONE (192)
CYTARABINE (168)
APIXABAN (158)
PREDNISONE (157)
BEVACIZUMAB (144)
VINCRISTINE (140)
Which DEFIBROTIDE Alternatives Have Lower Pulmonary haemorrhage Risk?
DEFIBROTIDE vs DEFLAZACORT
DEFIBROTIDE vs DEGARELIX
DEFIBROTIDE vs DELAFLOXACIN MEGLUMINE
DEFIBROTIDE vs DELAMANID
DEFIBROTIDE vs DELANDISTROGENE MOXEPARVOVEC-ROKL