Does DENOSUMAB Cause Hypocalcaemia? 2,345 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,345 reports of Hypocalcaemia have been filed in association with DENOSUMAB (Bilprevda). This represents 1.6% of all adverse event reports for DENOSUMAB.
2,345
Reports of Hypocalcaemia with DENOSUMAB
1.6%
of all DENOSUMAB reports
237
Deaths
1,313
Hospitalizations
How Dangerous Is Hypocalcaemia From DENOSUMAB?
Of the 2,345 reports, 237 (10.1%) resulted in death, 1,313 (56.0%) required hospitalization, and 191 (8.1%) were considered life-threatening.
Is Hypocalcaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DENOSUMAB. However, 2,345 reports have been filed with the FAERS database.
What Other Side Effects Does DENOSUMAB Cause?
Off label use (34,612)
Death (16,545)
Osteonecrosis of jaw (8,438)
Arthralgia (5,890)
Pain in extremity (4,541)
Back pain (4,465)
Pain (4,102)
Product storage error (3,621)
Fall (3,322)
Fatigue (3,009)
What Other Drugs Cause Hypocalcaemia?
OMEPRAZOLE (966)
PANTOPRAZOLE (935)
PARATHYROID HORMONE (784)
ZOLEDRONIC ACID (513)
CINACALCET (468)
ESOMEPRAZOLE (451)
FUROSEMIDE (429)
DEXAMETHASONE (368)
PREDNISONE (352)
LENALIDOMIDE (339)
Which DENOSUMAB Alternatives Have Lower Hypocalcaemia Risk?
DENOSUMAB vs DEOXYCHOLIC ACID
DENOSUMAB vs DEPAKINE CHRONO
DENOSUMAB vs DEPAKOTE
DENOSUMAB vs DEPO-PROVERA
DENOSUMAB vs DERMATOPHAGOIDES FARINAE