DESOGESTREL: 592 Adverse Event Reports & Safety Profile
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592
Total FAERS Reports
29 (4.9%)
Deaths Reported
242
Hospitalizations
592
As Primary/Secondary Suspect
42
Life-Threatening
44
Disabilities
First Report: 19981001 · Latest Report: 20250901
What Are the Most Common DESOGESTREL Side Effects?
#1 Most Reported
Off label use
42 reports (7.1%)
#2 Most Reported
Vomiting
37 reports (6.3%)
#3 Most Reported
Maternal exposure during pregnancy
36 reports (6.1%)
All DESOGESTREL Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 42 | 7.1% | 11 | 21 |
| Vomiting | 37 | 6.3% | 6 | 18 |
| Maternal exposure during pregnancy | 36 | 6.1% | 8 | 11 |
| Pyrexia | 32 | 5.4% | 8 | 24 |
| Dyspnoea | 31 | 5.2% | 8 | 15 |
| Nausea | 31 | 5.2% | 6 | 16 |
| Drug ineffective | 30 | 5.1% | 8 | 15 |
| Fatigue | 29 | 4.9% | 8 | 18 |
| Pulmonary embolism | 28 | 4.7% | 1 | 21 |
| Asthenia | 27 | 4.6% | 10 | 16 |
| Pruritus | 27 | 4.6% | 8 | 15 |
| Weight increased | 27 | 4.6% | 9 | 16 |
| Headache | 26 | 4.4% | 7 | 18 |
| Hypertension | 26 | 4.4% | 7 | 9 |
| Intentional overdose | 26 | 4.4% | 0 | 24 |
| Abdominal discomfort | 25 | 4.2% | 10 | 19 |
| Meningioma | 25 | 4.2% | 0 | 9 |
| Pain | 25 | 4.2% | 8 | 16 |
| Haemorrhage | 24 | 4.1% | 0 | 14 |
| Toxicity to various agents | 24 | 4.1% | 0 | 24 |
Who Reports DESOGESTREL Side Effects? Age & Gender Data
Gender: 96.4% female, 3.6% male. Average age: 33.5 years. Most reports from: FR. View detailed demographics →
Is DESOGESTREL Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2003 | 2 | 0 | 2 |
| 2007 | 4 | 0 | 2 |
| 2008 | 11 | 0 | 9 |
| 2009 | 3 | 0 | 1 |
| 2010 | 2 | 0 | 0 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 0 |
| 2013 | 3 | 1 | 2 |
| 2014 | 16 | 0 | 11 |
| 2015 | 33 | 2 | 6 |
| 2016 | 26 | 0 | 12 |
| 2017 | 49 | 0 | 23 |
| 2018 | 42 | 0 | 32 |
| 2019 | 69 | 0 | 21 |
| 2020 | 35 | 0 | 13 |
| 2021 | 14 | 1 | 5 |
| 2022 | 58 | 11 | 25 |
| 2023 | 38 | 0 | 14 |
| 2024 | 18 | 0 | 6 |
| 2025 | 18 | 0 | 14 |
What Is DESOGESTREL Used For?
| Indication | Reports |
|---|---|
| Contraception | 264 |
| Product used for unknown indication | 126 |
| Oral contraception | 71 |
| Hormonal contraception | 15 |
| Polycystic ovaries | 13 |
| Endometriosis | 8 |
| Menometrorrhagia | 8 |
| Foetal exposure during pregnancy | 7 |
| Menstrual cycle management | 6 |
DESOGESTREL vs Alternatives: Which Is Safer?
DESOGESTREL vs DESOGESTREL\ETHINYL ESTRADIOL
DESOGESTREL vs DESONIDE
DESOGESTREL vs DESOXIMETASONE
DESOGESTREL vs DESVENLAFAXINE
DESOGESTREL vs DETROL
DESOGESTREL vs DEUCRAVACITINIB
DESOGESTREL vs DEUTETRABENAZINE
DESOGESTREL vs DEUTIVACAFTOR\TEZACAFTOR\VANZACAFTOR
DESOGESTREL vs DEVICE
DESOGESTREL vs DEXAMETHASONE
Official FDA Label for DESOGESTREL
Official prescribing information from the FDA-approved drug label.