DIHYDROCODEINE: 1,081 Adverse Event Reports & Safety Profile
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1,081
Total FAERS Reports
351 (32.5%)
Deaths Reported
306
Hospitalizations
1,081
As Primary/Secondary Suspect
85
Life-Threatening
85
Disabilities
First Report: 1997 · Latest Report: 20250302
What Are the Most Common DIHYDROCODEINE Side Effects?
#1 Most Reported
Toxicity to various agents
206 reports (19.1%)
#2 Most Reported
Overdose
158 reports (14.6%)
#3 Most Reported
Drug dependence
128 reports (11.8%)
All DIHYDROCODEINE Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Toxicity to various agents | 206 | 19.1% | 167 | 34 |
| Overdose | 158 | 14.6% | 57 | 44 |
| Drug dependence | 128 | 11.8% | 22 | 4 |
| Drug abuse | 73 | 6.8% | 40 | 22 |
| Death | 72 | 6.7% | 71 | 7 |
| Constipation | 70 | 6.5% | 1 | 37 |
| Intentional product misuse | 62 | 5.7% | 13 | 13 |
| Somnolence | 52 | 4.8% | 5 | 25 |
| Completed suicide | 51 | 4.7% | 51 | 3 |
| Intentional overdose | 48 | 4.4% | 17 | 17 |
| Nausea | 45 | 4.2% | 0 | 6 |
| Seizure | 44 | 4.1% | 0 | 12 |
| Abdominal pain | 43 | 4.0% | 0 | 41 |
| Foetal exposure during pregnancy | 42 | 3.9% | 3 | 12 |
| Diarrhoea | 38 | 3.5% | 1 | 14 |
| Pain | 38 | 3.5% | 5 | 2 |
| Fall | 36 | 3.3% | 4 | 11 |
| Suicide attempt | 35 | 3.2% | 2 | 21 |
| Fatigue | 34 | 3.2% | 1 | 2 |
| Off label use | 33 | 3.1% | 1 | 27 |
Who Reports DIHYDROCODEINE Side Effects? Age & Gender Data
Gender: 47.2% female, 52.8% male. Average age: 46.8 years. Most reports from: GB. View detailed demographics →
Is DIHYDROCODEINE Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 2 | 1 | 1 |
| 2003 | 8 | 7 | 0 |
| 2004 | 2 | 2 | 0 |
| 2005 | 12 | 0 | 5 |
| 2006 | 1 | 0 | 0 |
| 2007 | 5 | 3 | 1 |
| 2009 | 17 | 1 | 16 |
| 2010 | 15 | 1 | 11 |
| 2011 | 2 | 2 | 0 |
| 2012 | 14 | 8 | 4 |
| 2013 | 21 | 14 | 7 |
| 2014 | 38 | 0 | 27 |
| 2015 | 40 | 18 | 3 |
| 2016 | 26 | 8 | 2 |
| 2017 | 11 | 4 | 1 |
| 2018 | 50 | 5 | 18 |
| 2019 | 27 | 6 | 18 |
| 2020 | 58 | 14 | 30 |
| 2021 | 18 | 0 | 12 |
| 2022 | 16 | 10 | 6 |
| 2023 | 19 | 2 | 17 |
| 2024 | 2 | 1 | 0 |
| 2025 | 18 | 0 | 2 |
What Is DIHYDROCODEINE Used For?
| Indication | Reports |
|---|---|
| Product used for unknown indication | 677 |
| Pain | 84 |
| Back pain | 32 |
| Visual impairment | 26 |
| Cough | 13 |
| Suicide attempt | 13 |
| Drug abuse | 9 |
| Gait disturbance | 8 |
| Analgesic therapy | 7 |
| Bronchitis | 7 |
DIHYDROCODEINE vs Alternatives: Which Is Safer?
DIHYDROCODEINE vs DIHYDROERGOTAMINE
DIHYDROCODEINE vs DILANTIN
DIHYDROCODEINE vs DILAUDID
DIHYDROCODEINE vs DILTIAZEM
DIHYDROCODEINE vs DIMENHYDRINATE
DIHYDROCODEINE vs DIMETHICONE
DIHYDROCODEINE vs DIMETHICONE\LOPERAMIDE
DIHYDROCODEINE vs DIMETHINDENE
DIHYDROCODEINE vs DIMETHYL
DIHYDROCODEINE vs DIMETHYL SULFONE
Official FDA Label for DIHYDROCODEINE
Official prescribing information from the FDA-approved drug label.