DINUTUXIMAB for Neuroblastoma: Side Effects & Safety Data
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There are 354 adverse event reports in the FDA FAERS database where DINUTUXIMAB was used for Neuroblastoma.
Most Reported Side Effects for DINUTUXIMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Pyrexia | 144 | 21.3% | 37 | 59 |
| Off label use | 95 | 14.1% | 17 | 30 |
| Neuroblastoma recurrent | 76 | 11.2% | 49 | 11 |
| Pain | 74 | 11.0% | 5 | 28 |
| Abdominal pain | 60 | 8.9% | 17 | 17 |
| Hypotension | 55 | 8.1% | 11 | 35 |
| Neuroblastoma | 49 | 7.3% | 30 | 5 |
| Anaemia | 47 | 7.0% | 24 | 8 |
| Aspartate aminotransferase increased | 46 | 6.8% | 11 | 11 |
| Alanine aminotransferase increased | 43 | 6.4% | 9 | 12 |
| Hypoxia | 42 | 6.2% | 5 | 17 |
| Vomiting | 42 | 6.2% | 5 | 15 |
| Hypoalbuminaemia | 41 | 6.1% | 10 | 11 |
| Diarrhoea | 40 | 5.9% | 7 | 23 |
| Pain in extremity | 40 | 5.9% | 10 | 19 |
Other Indications for DINUTUXIMAB
Neuroblastoma recurrent (102)
Product used for unknown indication (99)
Small cell lung cancer (37)
Metastases to bone (23)
Chemotherapy (16)
Metastases to liver (16)
Ganglioneuroblastoma (7)
Other Drugs Used for Neuroblastoma
CYCLOPHOSPHAMIDE (1,109)
ETOPOSIDE (1,061)
DOXORUBICIN (725)
CARBOPLATIN (671)
VINCRISTINE (668)
CISPLATIN (633)
MELPHALAN (495)
TOPOTECAN (443)
BUSULFAN (252)
TEMOZOLOMIDE (250)