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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

DIPHENHYDRAMINE: Side Effect Reports by Year

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Year-by-year breakdown of FAERS adverse event reports for DIPHENHYDRAMINE. Total: 25,827 reports.

Year Reports Deaths Hospitalizations Death Rate
2000 5 1 2 20.0%
2001 15 3 2 20.0%
2002 10 3 2 30.0%
2003 8 3 3 37.5%
2004 11 3 1 27.3%
2005 15 3 5 20.0%
2006 10 5 3 50.0%
2007 17 7 6 41.2%
2008 27 13 12 48.1%
2009 27 5 15 18.5%
2010 29 9 9 31.0%
2011 37 14 12 37.8%
2012 395 312 27 79.0%
2013 396 291 47 73.5%
2014 378 66 99 17.5%
2015 446 130 110 29.1%
2016 461 147 117 31.9%
2017 599 252 123 42.1%
2018 574 266 144 46.3%
2019 478 175 157 36.6%
2020 487 247 137 50.7%
2021 434 143 119 32.9%
2022 718 131 122 18.2%
2023 452 154 126 34.1%
2024 204 5 66 2.5%
2025 116 3 18 2.6%
Total 25,827 10,508 6,849 40.7%

FDA approval date: Approved Prior to Jan 1, 1982.

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