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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

DIPHENHYDRAMINE vs DIROXIMEL: Which Drug Is Safer?

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DIPHENHYDRAMINE vs DIROXIMEL: Safety Overview

Metric DIPHENHYDRAMINE DIROXIMEL
Total FAERS Reports 25,827 10,626
Deaths Reported 10,508 305
Death Rate 40.7% 2.9%
Hospitalizations 6,849 2,113
Average Patient Age 44.7 yrs 52.8 yrs
% Female Patients 72.2% 79.0%
FDA Approval Date Approved Prior to Jan 1, 1982 Nov 12, 2025
Manufacturer Whole Foods Market, INC. Biogen Inc.
Route ORAL ORAL
Marketing Status Discontinued Prescription