DISTIGMINE: 310 Adverse Event Reports & Safety Profile
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310
Total FAERS Reports
262 (84.5%)
Deaths Reported
190
Hospitalizations
310
As Primary/Secondary Suspect
142
Life-Threatening
177
Disabilities
Active Ingredient: DISTIGMINE BROMIDE ·
First Report: 20060830 · Latest Report: 20230310
What Are the Most Common DISTIGMINE Side Effects?
#1 Most Reported
Abdominal distension
210 reports (67.7%)
#2 Most Reported
Sepsis
205 reports (66.1%)
#3 Most Reported
Hyponatraemia
205 reports (66.1%)
All DISTIGMINE Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Abdominal distension | 210 | 67.7% | 210 | 122 |
| Hyponatraemia | 205 | 66.1% | 205 | 110 |
| Sepsis | 205 | 66.1% | 203 | 106 |
| Appendicitis | 204 | 65.8% | 204 | 110 |
| Ascites | 204 | 65.8% | 204 | 110 |
| Multiple organ dysfunction syndrome | 203 | 65.5% | 203 | 108 |
| Appendicolith | 202 | 65.2% | 202 | 108 |
| General physical health deterioration | 201 | 64.8% | 201 | 106 |
| Stress | 201 | 64.8% | 201 | 106 |
| Abdominal pain | 197 | 63.6% | 196 | 109 |
| Cardiogenic shock | 196 | 63.2% | 196 | 102 |
| Constipation | 195 | 62.9% | 190 | 107 |
| Vomiting | 192 | 61.9% | 191 | 105 |
| Nausea | 190 | 61.3% | 189 | 101 |
| Ventricular fibrillation | 188 | 60.7% | 188 | 109 |
| Off label use | 185 | 59.7% | 185 | 109 |
| Blood phosphorus increased | 144 | 46.5% | 144 | 105 |
| Condition aggravated | 143 | 46.1% | 143 | 106 |
| Somnolence | 141 | 45.5% | 140 | 107 |
| Dry mouth | 133 | 42.9% | 133 | 99 |
Who Reports DISTIGMINE Side Effects? Age & Gender Data
Gender: 5.8% female, 94.2% male. Average age: 79.0 years. Most reports from: CA. View detailed demographics →
Is DISTIGMINE Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2006 | 1 | 1 | 0 |
| 2011 | 1 | 1 | 0 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 2 | 0 |
| 2014 | 3 | 0 | 1 |
| 2015 | 2 | 2 | 2 |
| 2016 | 3 | 1 | 3 |
| 2017 | 6 | 0 | 6 |
| 2018 | 2 | 0 | 0 |
| 2019 | 7 | 3 | 1 |
| 2020 | 54 | 52 | 46 |
| 2021 | 17 | 10 | 7 |
| 2022 | 1 | 0 | 1 |
| 2023 | 5 | 2 | 4 |
What Is DISTIGMINE Used For?
| Indication | Reports |
|---|---|
| Dyspnoea | 223 |
| Product used for unknown indication | 62 |
| Off label use | 53 |
| Neurogenic bladder | 9 |
| Dysuria | 6 |
DISTIGMINE vs Alternatives: Which Is Safer?
DISTIGMINE vs DISULFIRAM
DISTIGMINE vs DIVALPROEX
DISTIGMINE vs DOBUTAMINE
DISTIGMINE vs DOBUTAMINE\DOBUTAMINE
DISTIGMINE vs DOCETAXEL
DISTIGMINE vs DOCETAXEL ANHYDROUS
DISTIGMINE vs DOCETAXEL\DOCETAXEL ANHYDROUS
DISTIGMINE vs DOCONEXENT
DISTIGMINE vs DOCONEXENT\ICOSAPENT
DISTIGMINE vs DOCONEXENT\ICOSAPENT\PHOSPHATIDYL SERINE
Official FDA Label for DISTIGMINE
Official prescribing information from the FDA-approved drug label.