DONEPEZIL\MEMANTINE: 335 Adverse Event Reports & Safety Profile
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335
Total FAERS Reports
33 (9.9%)
Deaths Reported
42
Hospitalizations
335
As Primary/Secondary Suspect
1
Life-Threatening
3
Disabilities
Active Ingredient: DONEPEZIL HYDROCHLORIDE\MEMANTINE HYDROCHLORIDE ·
First Report: 20120622 · Latest Report: 20250724
What Are the Most Common DONEPEZIL\MEMANTINE Side Effects?
#1 Most Reported
Dizziness
49 reports (14.6%)
#2 Most Reported
Nausea
28 reports (8.4%)
#3 Most Reported
Vomiting
24 reports (7.2%)
All DONEPEZIL\MEMANTINE Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Dizziness | 49 | 14.6% | 0 | 3 |
| Nausea | 28 | 8.4% | 0 | 1 |
| Vomiting | 24 | 7.2% | 0 | 5 |
| Diarrhoea | 23 | 6.9% | 0 | 0 |
| Confusional state | 20 | 6.0% | 0 | 2 |
| Drug ineffective | 18 | 5.4% | 0 | 0 |
| Fall | 15 | 4.5% | 3 | 7 |
| Fatigue | 15 | 4.5% | 0 | 1 |
| Off label use | 15 | 4.5% | 0 | 1 |
| Feeling abnormal | 14 | 4.2% | 0 | 1 |
| Hallucination | 14 | 4.2% | 0 | 1 |
| Malaise | 14 | 4.2% | 0 | 0 |
| Decreased appetite | 13 | 3.9% | 0 | 1 |
| Headache | 13 | 3.9% | 0 | 2 |
| Death | 11 | 3.3% | 11 | 2 |
| Dementia | 9 | 2.7% | 0 | 2 |
| Expired product administered | 9 | 2.7% | 0 | 0 |
| Agitation | 8 | 2.4% | 0 | 3 |
| Asthenia | 8 | 2.4% | 1 | 2 |
| Completed suicide | 8 | 2.4% | 8 | 2 |
Who Reports DONEPEZIL\MEMANTINE Side Effects? Age & Gender Data
Gender: 55.1% female, 44.9% male. Average age: 78.9 years. Most reports from: US. View detailed demographics →
Is DONEPEZIL\MEMANTINE Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2012 | 1 | 0 | 1 |
| 2015 | 6 | 0 | 3 |
| 2016 | 31 | 1 | 6 |
| 2017 | 41 | 4 | 8 |
| 2018 | 15 | 1 | 2 |
| 2019 | 12 | 2 | 1 |
| 2020 | 7 | 4 | 2 |
| 2021 | 2 | 0 | 0 |
| 2022 | 6 | 1 | 3 |
| 2023 | 5 | 1 | 1 |
| 2024 | 5 | 2 | 2 |
| 2025 | 2 | 1 | 0 |
What Is DONEPEZIL\MEMANTINE Used For?
| Indication | Reports |
|---|---|
| Product used for unknown indication | 135 |
| Dementia alzheimer's type | 85 |
| Dementia | 60 |
| Amnesia | 17 |
| Memory impairment | 13 |
DONEPEZIL\MEMANTINE vs Alternatives: Which Is Safer?
DONEPEZIL\MEMANTINE vs DONEPEZIL\OMEPRAZOLE\OMEPRAZOLE
DONEPEZIL\MEMANTINE vs DONOR HUMAN STOOL
DONEPEZIL\MEMANTINE vs DOPAMINE
DONEPEZIL\MEMANTINE vs DOPAMINE\DOPAMINE
DONEPEZIL\MEMANTINE vs DORAVIRINE
DONEPEZIL\MEMANTINE vs DORAVIRINE\LAMIVUDINE\TENOFOVIR DISOPROXIL
DONEPEZIL\MEMANTINE vs DORIPENEM
DONEPEZIL\MEMANTINE vs DORNASE ALFA
DONEPEZIL\MEMANTINE vs DORZOLAMIDE
DONEPEZIL\MEMANTINE vs DORZOLAMIDE\TIMOLOL
Official FDA Label for DONEPEZIL\MEMANTINE
Official prescribing information from the FDA-approved drug label.