Does DORNASE ALFA Cause Dyspnoea? 246 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 246 reports of Dyspnoea have been filed in association with DORNASE ALFA (Pulmozyme). This represents 4.5% of all adverse event reports for DORNASE ALFA.
246
Reports of Dyspnoea with DORNASE ALFA
4.5%
of all DORNASE ALFA reports
24
Deaths
197
Hospitalizations
How Dangerous Is Dyspnoea From DORNASE ALFA?
Of the 246 reports, 24 (9.8%) resulted in death, 197 (80.1%) required hospitalization, and 28 (11.4%) were considered life-threatening.
Is Dyspnoea Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DORNASE ALFA. However, 246 reports have been filed with the FAERS database.
What Other Side Effects Does DORNASE ALFA Cause?
No adverse event (889)
Cystic fibrosis (565)
Off label use (522)
Hospitalisation (512)
Pneumonia (377)
Condition aggravated (304)
Infective pulmonary exacerbation of cystic fibrosis (245)
Product storage error (242)
Death (225)
Cough (195)
What Other Drugs Cause Dyspnoea?
ALBUTEROL (21,856)
TREPROSTINIL (16,348)
AMBRISENTAN (13,367)
PREDNISONE (12,830)
BUDESONIDE\FORMOTEROL (11,158)
TIOTROPIUM (10,863)
ADALIMUMAB (10,547)
DUPILUMAB (10,310)
FLUTICASONE\SALMETEROL (9,783)
MEPOLIZUMAB (9,192)
Which DORNASE ALFA Alternatives Have Lower Dyspnoea Risk?
DORNASE ALFA vs DORZOLAMIDE
DORNASE ALFA vs DORZOLAMIDE\TIMOLOL
DORNASE ALFA vs DOSTARLIMAB
DORNASE ALFA vs DOSTARLIMAB-GXLY
DORNASE ALFA vs DOTATATE GALLIUM GA-68