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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

DOXYCYCLINE\DOXYCYCLINE HYCLATE: 1,034 Adverse Event Reports & Safety Profile

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1,034
Total FAERS Reports
213 (20.6%)
Deaths Reported
433
Hospitalizations
1,034
As Primary/Secondary Suspect
211
Life-Threatening
210
Disabilities

First Report: 19680816 · Latest Report: 20240922

What Are the Most Common DOXYCYCLINE\DOXYCYCLINE HYCLATE Side Effects?

#1 Most Reported
Drug ineffective
161 reports (15.6%)
#2 Most Reported
Off label use
147 reports (14.2%)
#3 Most Reported
Pruritus
141 reports (13.6%)

All DOXYCYCLINE\DOXYCYCLINE HYCLATE Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Drug ineffective 161 15.6% 58 85
Off label use 147 14.2% 44 96
Pruritus 141 13.6% 100 113
Hypertension 140 13.5% 103 135
Wheezing 134 13.0% 96 128
Rash 133 12.9% 93 112
Condition aggravated 132 12.8% 56 86
Malaise 127 12.3% 96 114
Hypoaesthesia 126 12.2% 107 120
Fatigue 124 12.0% 99 111
Mobility decreased 123 11.9% 106 117
Liver disorder 121 11.7% 103 109
Pyrexia 121 11.7% 103 115
Type 2 diabetes mellitus 121 11.7% 107 118
Infection 119 11.5% 101 113
Joint swelling 119 11.5% 100 113
Vomiting 119 11.5% 97 109
Rheumatic fever 118 11.4% 104 115
Infusion related reaction 117 11.3% 103 113
Hypersensitivity 116 11.2% 97 108

Who Reports DOXYCYCLINE\DOXYCYCLINE HYCLATE Side Effects? Age & Gender Data

Gender: 58.5% female, 41.5% male. Average age: 51.6 years. Most reports from: US. View detailed demographics →

Is DOXYCYCLINE\DOXYCYCLINE HYCLATE Getting Safer? Reports by Year

YearReportsDeathsHosp.
2002 1 0 1
2005 1 0 0
2010 1 0 1
2011 1 0 1
2013 3 0 2
2015 1 1 1
2016 1 0 1
2017 2 0 0
2018 1 0 0
2019 2 1 0
2020 1 0 0
2021 4 0 1
2022 7 0 2
2023 32 0 12
2024 200 1 63

View full timeline →

What Is DOXYCYCLINE\DOXYCYCLINE HYCLATE Used For?

IndicationReports
Product used for unknown indication 306
Sexually transmitted disease 33
Infection 32
Acne 29
Rheumatoid arthritis 26
Pneumonia 25
Ill-defined disorder 24
Lower respiratory tract infection 24
Hidradenitis 22
Antibiotic therapy 21

DOXYCYCLINE\DOXYCYCLINE HYCLATE vs Alternatives: Which Is Safer?

DOXYCYCLINE\DOXYCYCLINE HYCLATE vs DOXYLAMINE DOXYCYCLINE\DOXYCYCLINE HYCLATE vs DOXYLAMINE\PYRIDOXINE DOXYCYCLINE\DOXYCYCLINE HYCLATE vs DRONABINOL DOXYCYCLINE\DOXYCYCLINE HYCLATE vs DRONEDARONE DOXYCYCLINE\DOXYCYCLINE HYCLATE vs DROPERIDOL DOXYCYCLINE\DOXYCYCLINE HYCLATE vs DROSPIRENONE DOXYCYCLINE\DOXYCYCLINE HYCLATE vs DROSPIRENONE\ESTETROL DOXYCYCLINE\DOXYCYCLINE HYCLATE vs DROSPIRENONE\ESTRADIOL DOXYCYCLINE\DOXYCYCLINE HYCLATE vs DROSPIRENONE\ETHINYL ESTRADIOL DOXYCYCLINE\DOXYCYCLINE HYCLATE vs DROSPIRENONE\ETHINYL ESTRADIOL\LEVOMEFOLATE

Official FDA Label for DOXYCYCLINE\DOXYCYCLINE HYCLATE

Official prescribing information from the FDA-approved drug label.