Does ECULIZUMAB Cause Bacteraemia? 132 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 132 reports of Bacteraemia have been filed in association with ECULIZUMAB (SOLIRIS). This represents 0.3% of all adverse event reports for ECULIZUMAB.
132
Reports of Bacteraemia with ECULIZUMAB
0.3%
of all ECULIZUMAB reports
23
Deaths
90
Hospitalizations
How Dangerous Is Bacteraemia From ECULIZUMAB?
Of the 132 reports, 23 (17.4%) resulted in death, 90 (68.2%) required hospitalization, and 10 (7.6%) were considered life-threatening.
Is Bacteraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ECULIZUMAB. However, 132 reports have been filed with the FAERS database.
What Other Side Effects Does ECULIZUMAB Cause?
Fatigue (4,858)
Off label use (4,228)
Haemoglobin decreased (3,028)
Headache (2,699)
Death (2,221)
Pyrexia (1,948)
Dyspnoea (1,819)
Asthenia (1,732)
Drug ineffective (1,644)
Nausea (1,579)
What Other Drugs Cause Bacteraemia?
CYCLOPHOSPHAMIDE (705)
RITUXIMAB (631)
PREDNISONE (620)
TACROLIMUS (593)
MYCOPHENOLATE MOFETIL (524)
METHOTREXATE (501)
DEXAMETHASONE (486)
VINCRISTINE (470)
CYTARABINE (445)
ETOPOSIDE (417)
Which ECULIZUMAB Alternatives Have Lower Bacteraemia Risk?
ECULIZUMAB vs EDARAVONE
ECULIZUMAB vs EDETATE
ECULIZUMAB vs EDOXABAN
ECULIZUMAB vs EDOXABAN TOSILATE
ECULIZUMAB vs EFALIZUMAB