Does ECULIZUMAB Cause Endocarditis? 49 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 49 reports of Endocarditis have been filed in association with ECULIZUMAB (SOLIRIS). This represents 0.1% of all adverse event reports for ECULIZUMAB.
49
Reports of Endocarditis with ECULIZUMAB
0.1%
of all ECULIZUMAB reports
17
Deaths
39
Hospitalizations
How Dangerous Is Endocarditis From ECULIZUMAB?
Of the 49 reports, 17 (34.7%) resulted in death, 39 (79.6%) required hospitalization, and 3 (6.1%) were considered life-threatening.
Is Endocarditis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ECULIZUMAB. However, 49 reports have been filed with the FAERS database.
What Other Side Effects Does ECULIZUMAB Cause?
Fatigue (4,858)
Off label use (4,228)
Haemoglobin decreased (3,028)
Headache (2,699)
Death (2,221)
Pyrexia (1,948)
Dyspnoea (1,819)
Asthenia (1,732)
Drug ineffective (1,644)
Nausea (1,579)
What Other Drugs Cause Endocarditis?
PREDNISONE (224)
PREDNISOLONE (176)
METHOTREXATE (170)
MYCOPHENOLATE MOFETIL (167)
DEXAMETHASONE (156)
TACROLIMUS (153)
RITUXIMAB (128)
CYCLOPHOSPHAMIDE (125)
VANCOMYCIN (110)
TOCILIZUMAB (104)
Which ECULIZUMAB Alternatives Have Lower Endocarditis Risk?
ECULIZUMAB vs EDARAVONE
ECULIZUMAB vs EDETATE
ECULIZUMAB vs EDOXABAN
ECULIZUMAB vs EDOXABAN TOSILATE
ECULIZUMAB vs EFALIZUMAB