Does ECULIZUMAB Cause Eosinophilia? 20 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Eosinophilia have been filed in association with ECULIZUMAB (SOLIRIS). This represents 0.1% of all adverse event reports for ECULIZUMAB.
20
Reports of Eosinophilia with ECULIZUMAB
0.1%
of all ECULIZUMAB reports
5
Deaths
14
Hospitalizations
How Dangerous Is Eosinophilia From ECULIZUMAB?
Of the 20 reports, 5 (25.0%) resulted in death, 14 (70.0%) required hospitalization, and 7 (35.0%) were considered life-threatening.
Is Eosinophilia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ECULIZUMAB. However, 20 reports have been filed with the FAERS database.
What Other Side Effects Does ECULIZUMAB Cause?
Fatigue (4,858)
Off label use (4,228)
Haemoglobin decreased (3,028)
Headache (2,699)
Death (2,221)
Pyrexia (1,948)
Dyspnoea (1,819)
Asthenia (1,732)
Drug ineffective (1,644)
Nausea (1,579)
What Other Drugs Cause Eosinophilia?
ALBUTEROL (1,054)
PREDNISONE (815)
CLOZAPINE (806)
MONTELUKAST (741)
PANTOPRAZOLE (709)
VANCOMYCIN (695)
MEPOLIZUMAB (606)
ALLOPURINOL (554)
BUDESONIDE\FORMOTEROL (553)
PIPERACILLIN\TAZOBACTAM (530)
Which ECULIZUMAB Alternatives Have Lower Eosinophilia Risk?
ECULIZUMAB vs EDARAVONE
ECULIZUMAB vs EDETATE
ECULIZUMAB vs EDOXABAN
ECULIZUMAB vs EDOXABAN TOSILATE
ECULIZUMAB vs EFALIZUMAB