Does ECULIZUMAB Cause Extravascular haemolysis? 182 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 182 reports of Extravascular haemolysis have been filed in association with ECULIZUMAB (SOLIRIS). This represents 0.4% of all adverse event reports for ECULIZUMAB.
182
Reports of Extravascular haemolysis with ECULIZUMAB
0.4%
of all ECULIZUMAB reports
3
Deaths
28
Hospitalizations
How Dangerous Is Extravascular haemolysis From ECULIZUMAB?
Of the 182 reports, 3 (1.6%) resulted in death, 28 (15.4%) required hospitalization.
Is Extravascular haemolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ECULIZUMAB. However, 182 reports have been filed with the FAERS database.
What Other Side Effects Does ECULIZUMAB Cause?
Fatigue (4,858)
Off label use (4,228)
Haemoglobin decreased (3,028)
Headache (2,699)
Death (2,221)
Pyrexia (1,948)
Dyspnoea (1,819)
Asthenia (1,732)
Drug ineffective (1,644)
Nausea (1,579)
What Other Drugs Cause Extravascular haemolysis?
RAVULIZUMAB-CWVZ (99)
HUMAN IMMUNOGLOBULIN G (13)
SOLIRIS (11)
DANICOPAN (9)
OXALIPLATIN (7)
DICLOFENAC (5)
Which ECULIZUMAB Alternatives Have Lower Extravascular haemolysis Risk?
ECULIZUMAB vs EDARAVONE
ECULIZUMAB vs EDETATE
ECULIZUMAB vs EDOXABAN
ECULIZUMAB vs EDOXABAN TOSILATE
ECULIZUMAB vs EFALIZUMAB