Does ECULIZUMAB Cause Syncope? 136 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 136 reports of Syncope have been filed in association with ECULIZUMAB (SOLIRIS). This represents 0.3% of all adverse event reports for ECULIZUMAB.
136
Reports of Syncope with ECULIZUMAB
0.3%
of all ECULIZUMAB reports
11
Deaths
62
Hospitalizations
How Dangerous Is Syncope From ECULIZUMAB?
Of the 136 reports, 11 (8.1%) resulted in death, 62 (45.6%) required hospitalization, and 4 (2.9%) were considered life-threatening.
Is Syncope Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ECULIZUMAB. However, 136 reports have been filed with the FAERS database.
What Other Side Effects Does ECULIZUMAB Cause?
Fatigue (4,858)
Off label use (4,228)
Haemoglobin decreased (3,028)
Headache (2,699)
Death (2,221)
Pyrexia (1,948)
Dyspnoea (1,819)
Asthenia (1,732)
Drug ineffective (1,644)
Nausea (1,579)
What Other Drugs Cause Syncope?
AMBRISENTAN (2,140)
TREPROSTINIL (1,908)
ADALIMUMAB (1,795)
FUROSEMIDE (1,431)
LENALIDOMIDE (1,280)
BISOPROLOL (1,279)
METOPROLOL (1,251)
AMLODIPINE (1,224)
ASPIRIN (1,193)
SACUBITRIL\VALSARTAN (1,163)
Which ECULIZUMAB Alternatives Have Lower Syncope Risk?
ECULIZUMAB vs EDARAVONE
ECULIZUMAB vs EDETATE
ECULIZUMAB vs EDOXABAN
ECULIZUMAB vs EDOXABAN TOSILATE
ECULIZUMAB vs EFALIZUMAB