Does ECULIZUMAB Cause Thrombocytopenia? 432 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 432 reports of Thrombocytopenia have been filed in association with ECULIZUMAB (SOLIRIS). This represents 1.0% of all adverse event reports for ECULIZUMAB.
432
Reports of Thrombocytopenia with ECULIZUMAB
1.0%
of all ECULIZUMAB reports
82
Deaths
211
Hospitalizations
How Dangerous Is Thrombocytopenia From ECULIZUMAB?
Of the 432 reports, 82 (19.0%) resulted in death, 211 (48.8%) required hospitalization, and 27 (6.3%) were considered life-threatening.
Is Thrombocytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ECULIZUMAB. However, 432 reports have been filed with the FAERS database.
What Other Side Effects Does ECULIZUMAB Cause?
Fatigue (4,858)
Off label use (4,228)
Haemoglobin decreased (3,028)
Headache (2,699)
Death (2,221)
Pyrexia (1,948)
Dyspnoea (1,819)
Asthenia (1,732)
Drug ineffective (1,644)
Nausea (1,579)
What Other Drugs Cause Thrombocytopenia?
DEXAMETHASONE (5,873)
RITUXIMAB (4,810)
CYCLOPHOSPHAMIDE (4,669)
LENALIDOMIDE (4,584)
CARBOPLATIN (4,483)
METHOTREXATE (3,865)
DOXORUBICIN (3,638)
ETOPOSIDE (3,085)
VINCRISTINE (2,940)
OXALIPLATIN (2,886)
Which ECULIZUMAB Alternatives Have Lower Thrombocytopenia Risk?
ECULIZUMAB vs EDARAVONE
ECULIZUMAB vs EDETATE
ECULIZUMAB vs EDOXABAN
ECULIZUMAB vs EDOXABAN TOSILATE
ECULIZUMAB vs EFALIZUMAB