ENTRECTINIB for Metastases to central nervous system: Side Effects & Safety Data
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There are 25 adverse event reports in the FDA FAERS database where ENTRECTINIB was used for Metastases to central nervous system.
Most Reported Side Effects for ENTRECTINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Dizziness | 143 | 9.6% | 13 | 25 |
| Off label use | 137 | 9.2% | 20 | 10 |
| Death | 126 | 8.5% | 125 | 6 |
| Disease progression | 105 | 7.0% | 38 | 15 |
| Taste disorder | 68 | 4.6% | 7 | 9 |
| No adverse event | 65 | 4.4% | 0 | 1 |
| Constipation | 60 | 4.0% | 3 | 9 |
| Fatigue | 60 | 4.0% | 6 | 11 |
| Drug ineffective | 58 | 3.9% | 13 | 4 |
| Blood creatinine increased | 57 | 3.8% | 7 | 17 |
| Nausea | 56 | 3.8% | 3 | 11 |
| Renal impairment | 53 | 3.6% | 5 | 8 |
| Diarrhoea | 52 | 3.5% | 7 | 15 |
| Weight increased | 51 | 3.4% | 3 | 9 |
| Cardiac failure | 45 | 3.0% | 11 | 24 |
Other Indications for ENTRECTINIB
Non-small cell lung cancer (412)
Lung neoplasm malignant (339)
Product used for unknown indication (196)
Neoplasm (56)
Lung adenocarcinoma (54)
Neoplasm malignant (47)
Non-small cell lung cancer metastatic (41)
Bronchial carcinoma (23)
Pancreatic carcinoma metastatic (18)
Lung adenocarcinoma stage iv (16)
Other Drugs Used for Metastases to central nervous system
PEMBROLIZUMAB (267)
DEXAMETHASONE (201)
BEVACIZUMAB (195)
CARBOPLATIN (186)
CAPECITABINE (158)
OSIMERTINIB (147)
TRASTUZUMAB (141)
CABOZANTINIB S-MALATE (138)
ERLOTINIB (127)
PEMETREXED (123)