Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

ETHINYL ESTRADIOL\SEGESTERONE: 329 Adverse Event Reports & Safety Profile

Boost Your Natural Energy & Metabolism

Mitolyn — 6 exotic plants to unlock your body's fat-burning power. 90-day guarantee.

Try Mitolyn Now
329
Total FAERS Reports
1 (0.3%)
Deaths Reported
20
Hospitalizations
329
As Primary/Secondary Suspect
7
Life-Threatening
4
Disabilities

Active Ingredient: ETHINYL ESTRADIOL\SEGESTERONE ACETATE ·

First Report: 20130101 · Latest Report: 20250701

What Are the Most Common ETHINYL ESTRADIOL\SEGESTERONE Side Effects?

#1 Most Reported
Intermenstrual bleeding
40 reports (12.2%)
#2 Most Reported
Vaginal haemorrhage
33 reports (10.0%)
#3 Most Reported
Off label use
33 reports (10.0%)

All ETHINYL ESTRADIOL\SEGESTERONE Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Intermenstrual bleeding 40 12.2% 0 0
Off label use 33 10.0% 0 4
Vaginal haemorrhage 33 10.0% 0 1
Nausea 32 9.7% 0 1
Drug ineffective 24 7.3% 0 0
Headache 20 6.1% 0 1
Vaginal discharge 17 5.2% 0 0
Vomiting 14 4.3% 0 1
Device expulsion 13 4.0% 0 1
Pulmonary embolism 13 4.0% 0 11
Metrorrhagia 12 3.7% 0 0
Abdominal pain 11 3.3% 0 2
Depression 11 3.3% 0 0
Menstrual disorder 11 3.3% 0 1
Dysmenorrhoea 10 3.0% 0 0
Device colour issue 9 2.7% 0 0
Menstruation irregular 9 2.7% 0 0
Migraine 9 2.7% 0 0
Muscle spasms 9 2.7% 0 1
Vulvovaginal discomfort 9 2.7% 0 0

Who Reports ETHINYL ESTRADIOL\SEGESTERONE Side Effects? Age & Gender Data

Gender: 99.4% female, 0.6% male. Average age: 29.3 years. Most reports from: US. View detailed demographics →

Is ETHINYL ESTRADIOL\SEGESTERONE Getting Safer? Reports by Year

YearReportsDeathsHosp.
2013 1 0 0
2019 2 0 1
2020 57 1 2
2021 49 0 6
2022 38 0 2
2023 15 0 4
2024 22 0 2
2025 6 0 0

View full timeline →

What Is ETHINYL ESTRADIOL\SEGESTERONE Used For?

IndicationReports
Contraception 120
Product used for unknown indication 39
Heavy menstrual bleeding 7
Menstrual cycle management 5

ETHINYL ESTRADIOL\SEGESTERONE vs Alternatives: Which Is Safer?

ETHINYL ESTRADIOL\SEGESTERONE vs ETHIODIZED OIL ETHINYL ESTRADIOL\SEGESTERONE vs ETHIONAMIDE ETHINYL ESTRADIOL\SEGESTERONE vs ETHOSUXIMIDE ETHINYL ESTRADIOL\SEGESTERONE vs ETHYL ICOSAPENTATE ETHINYL ESTRADIOL\SEGESTERONE vs ETHYL LOFLAZEPATE ETHINYL ESTRADIOL\SEGESTERONE vs ETHYLENE GLYCOL ETHINYL ESTRADIOL\SEGESTERONE vs ETIFOXINE ETHINYL ESTRADIOL\SEGESTERONE vs ETIZOLAM ETHINYL ESTRADIOL\SEGESTERONE vs ETODOLAC ETHINYL ESTRADIOL\SEGESTERONE vs ETOMIDATE

Official FDA Label for ETHINYL ESTRADIOL\SEGESTERONE

Official prescribing information from the FDA-approved drug label.