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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

FENTANYL vs TRAMADOL: Which Drug Is Safer?

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FENTANYL vs TRAMADOL: Safety Overview

Metric FENTANYL TRAMADOL
Total FAERS Reports 94,485 75,664
Deaths Reported 42,491 14,555
Death Rate 45.0% 19.2%
Hospitalizations 15,153 19,235
Average Patient Age 48.2 yrs 50.7 yrs
% Female Patients 51.7% 55.6%
FDA Approval Date Approved Prior to Jan 1, 1982 Apr 4, 2024
Manufacturer Quality Care Products, LLC Vertical Pharmaceuticals, LLC
Route TRANSDERMAL ORAL
Marketing Status Prescription Discontinued