Does FLUOROURACIL Cause Neutropenia? 4,400 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 4,400 reports of Neutropenia have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 8.3% of all adverse event reports for FLUOROURACIL.
4,400
Reports of Neutropenia with FLUOROURACIL
8.3%
of all FLUOROURACIL reports
481
Deaths
1,155
Hospitalizations
How Dangerous Is Neutropenia From FLUOROURACIL?
Of the 4,400 reports, 481 (10.9%) resulted in death, 1,155 (26.3%) required hospitalization, and 352 (8.0%) were considered life-threatening.
Is Neutropenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 4,400 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
Anaemia (2,169)
What Other Drugs Cause Neutropenia?
CLOZAPINE (18,981)
CYCLOPHOSPHAMIDE (7,352)
LENALIDOMIDE (6,909)
RITUXIMAB (6,607)
PALBOCICLIB (6,423)
DEXAMETHASONE (6,050)
DOXORUBICIN (5,891)
CARBOPLATIN (5,314)
VINCRISTINE (4,982)
PACLITAXEL (4,553)
Which FLUOROURACIL Alternatives Have Lower Neutropenia Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE