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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

FOLATE: 925 Adverse Event Reports & Safety Profile

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925
Total FAERS Reports
71 (7.7%)
Deaths Reported
153
Hospitalizations
925
As Primary/Secondary Suspect
6
Life-Threatening
24
Disabilities
Oncora Pharma, LLC
Manufacturer

Active Ingredient: FOLATE SODIUM · Route: ORAL · Manufacturer: Oncora Pharma, LLC · HUMAN PRESCRIPTION DRUG · FDA Label: Available

First Report: 1999 · Latest Report: 20250101

What Are the Most Common FOLATE Side Effects?

#1 Most Reported
Pneumonia
506 reports (54.7%)
#2 Most Reported
Asthma
495 reports (53.5%)
#3 Most Reported
Vomiting
487 reports (52.6%)

All FOLATE Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Pneumonia 506 54.7% 1 22
Asthma 495 53.5% 0 21
Vomiting 487 52.7% 0 3
Drug hypersensitivity 484 52.3% 0 0
Oedema 473 51.1% 0 0
Dyspnoea 448 48.4% 0 12
Wheezing 435 47.0% 0 0
Pain 270 29.2% 0 14
Malaise 262 28.3% 0 0
Respiratory tract infection 262 28.3% 0 18
Chest pain 233 25.2% 0 0
Cough 226 24.4% 0 7
Foetal exposure during pregnancy 184 19.9% 28 28
Nasal oedema 141 15.2% 0 0
Off label use 71 7.7% 35 45
Congenital umbilical hernia 67 7.2% 0 0
Abortion spontaneous 52 5.6% 30 32
Maternal exposure during pregnancy 47 5.1% 19 24
Alanine aminotransferase increased 44 4.8% 31 44
Exposure during pregnancy 44 4.8% 18 18

Who Reports FOLATE Side Effects? Age & Gender Data

Gender: 74.3% female, 25.7% male. Average age: 52.3 years. Most reports from: CA. View detailed demographics →

Is FOLATE Getting Safer? Reports by Year

YearReportsDeathsHosp.
2009 1 0 1
2010 22 18 22
2011 2 0 2
2012 13 10 10
2013 1 0 0
2014 2 0 0
2015 2 0 1
2016 4 0 1
2017 34 11 12
2018 51 2 5
2019 1 0 1
2020 9 1 4
2021 6 0 0
2022 2 1 0
2023 4 0 2
2024 4 0 0
2025 1 0 0

View full timeline →

What Is FOLATE Used For?

IndicationReports
Product used for unknown indication 704
Supplementation therapy 60
Foetal exposure during pregnancy 20
Toxicity to various agents 18
Vitamin supplementation 18
Choriocarcinoma 6

FOLATE vs Alternatives: Which Is Safer?

FOLATE vs FOLIC ACID FOLATE vs FOLINIC ACID FOLATE vs FOLLICLE STIMULATING HORMONE BETA POLYPEPTIDE\LUTROPIN ALFA FOLATE vs FOLLITROPIN FOLATE vs FOLLITROPIN ALFA FOLATE vs FOLLITROPIN BETA FOLATE vs FOLLITROPIN\LUTEINIZING HORMONE FOLATE vs FOLLITROPIN\LUTROPIN ALFA FOLATE vs FONDAPARINUX FOLATE vs FORMOTEROL

Official FDA Label for FOLATE

Official prescribing information from the FDA-approved drug label.

Drug Description

Foltira is an orally administered prescription folate product.

FDA Approved Uses (Indications)

Foltira is for patients with unique nutritional needs requiring increased folate levels and Vitamin D supplementation due to Vitamin D deficiency.

Dosage & Administration

Take one tablet daily or as directed by a licensed medical practitioner. If you are pregnant or nursing ask a healthcare professional.

Warnings

Keep out of reach of children.

Precautions

Foltira should be administered under the supervision of a licensed medical practitioner.