GADOLINIUM: 1,315 Adverse Event Reports & Safety Profile
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1,315
Total FAERS Reports
38 (2.9%)
Deaths Reported
169
Hospitalizations
1,315
As Primary/Secondary Suspect
81
Life-Threatening
376
Disabilities
Hahnemann Laboratories, INC.
Manufacturer
Route: ORAL · Manufacturer: Hahnemann Laboratories, INC. · HUMAN OTC DRUG · FDA Label: Available
First Report: 19721020 · Latest Report: 20250708
What Are the Most Common GADOLINIUM Side Effects?
#1 Most Reported
Nephrogenic systemic fibrosis
370 reports (28.1%)
#2 Most Reported
Pain
310 reports (23.6%)
#3 Most Reported
Gadolinium deposition disease
310 reports (23.6%)
All GADOLINIUM Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Nephrogenic systemic fibrosis | 370 | 28.1% | 32 | 8 |
| Gadolinium deposition disease | 310 | 23.6% | 0 | 11 |
| Pain | 310 | 23.6% | 0 | 19 |
| Arthralgia | 303 | 23.0% | 0 | 26 |
| Fatigue | 278 | 21.1% | 0 | 20 |
| Burning sensation | 272 | 20.7% | 1 | 11 |
| Paraesthesia | 264 | 20.1% | 0 | 13 |
| Hypoaesthesia | 260 | 19.8% | 0 | 19 |
| Asthenia | 257 | 19.5% | 0 | 7 |
| Rash | 253 | 19.2% | 0 | 9 |
| Muscle spasms | 250 | 19.0% | 0 | 9 |
| Confusional state | 234 | 17.8% | 0 | 4 |
| Injury | 234 | 17.8% | 0 | 3 |
| Inflammation | 228 | 17.3% | 0 | 4 |
| Anxiety | 172 | 13.1% | 0 | 10 |
| Emotional distress | 161 | 12.2% | 0 | 2 |
| Mass | 152 | 11.6% | 0 | 0 |
| Contrast media deposition | 113 | 8.6% | 1 | 6 |
| Headache | 105 | 8.0% | 0 | 30 |
| Off label use | 95 | 7.2% | 1 | 5 |
Who Reports GADOLINIUM Side Effects? Age & Gender Data
Gender: 68.6% female, 31.4% male. Average age: 51.7 years. Most reports from: US. View detailed demographics →
Is GADOLINIUM Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2000 | 5 | 1 | 1 |
| 2001 | 3 | 0 | 0 |
| 2002 | 11 | 0 | 1 |
| 2003 | 16 | 3 | 0 |
| 2004 | 29 | 4 | 0 |
| 2005 | 39 | 5 | 0 |
| 2006 | 55 | 2 | 3 |
| 2007 | 38 | 3 | 1 |
| 2008 | 12 | 0 | 1 |
| 2009 | 15 | 0 | 4 |
| 2010 | 10 | 0 | 0 |
| 2011 | 6 | 0 | 1 |
| 2012 | 8 | 0 | 1 |
| 2013 | 18 | 0 | 5 |
| 2014 | 19 | 0 | 9 |
| 2015 | 43 | 0 | 14 |
| 2016 | 28 | 0 | 9 |
| 2017 | 43 | 1 | 12 |
| 2018 | 33 | 1 | 9 |
| 2019 | 15 | 0 | 5 |
| 2020 | 14 | 0 | 11 |
| 2021 | 14 | 1 | 6 |
| 2022 | 26 | 0 | 16 |
| 2023 | 9 | 0 | 2 |
| 2024 | 15 | 0 | 6 |
| 2025 | 7 | 0 | 4 |
What Is GADOLINIUM Used For?
| Indication | Reports |
|---|---|
| Product used for unknown indication | 526 |
| Nuclear magnetic resonance imaging | 261 |
| Diagnostic procedure | 193 |
| Angiogram | 153 |
| Magnetic resonance imaging | 125 |
| Computerised tomogram | 73 |
| Scan with contrast | 29 |
| Nuclear magnetic resonance imaging brain | 15 |
| Back pain | 13 |
| Headache | 13 |
GADOLINIUM vs Alternatives: Which Is Safer?
GADOLINIUM vs GADOPENTETATE DIMEGLUMINE
GADOLINIUM vs GADOPICLENOL
GADOLINIUM vs GADOTERATE MEGLUMINE
GADOLINIUM vs GADOTERIDOL
GADOLINIUM vs GADOVERSETAMIDE
GADOLINIUM vs GADOXETATE
GADOLINIUM vs GALANTAMINE
GADOLINIUM vs GALANTAMINE HYDROBROMIDE
GADOLINIUM vs GALCANEZUMAB
GADOLINIUM vs GALCANEZUMAB-GNLM
Official FDA Label for GADOLINIUM
Official prescribing information from the FDA-approved drug label.