GEFITINIB for Egfr gene mutation: Side Effects & Safety Data
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There are 97 adverse event reports in the FDA FAERS database where GEFITINIB was used for Egfr gene mutation.
Most Reported Side Effects for GEFITINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Malignant neoplasm progression | 1,651 | 35.2% | 217 | 160 |
| Drug resistance | 1,228 | 26.1% | 95 | 115 |
| Death | 590 | 12.6% | 589 | 50 |
| Diarrhoea | 393 | 8.4% | 73 | 114 |
| Rash | 318 | 6.8% | 48 | 66 |
| Metastases to central nervous system | 306 | 6.5% | 51 | 49 |
| Acquired gene mutation | 250 | 5.3% | 36 | 21 |
| Disease progression | 244 | 5.2% | 33 | 16 |
| Drug ineffective | 197 | 4.2% | 33 | 39 |
| Off label use | 166 | 3.5% | 37 | 40 |
| Decreased appetite | 163 | 3.5% | 44 | 55 |
| Metastases to bone | 147 | 3.1% | 19 | 14 |
| Nausea | 139 | 3.0% | 24 | 41 |
| Pleural effusion | 137 | 2.9% | 34 | 52 |
| Fatigue | 129 | 2.8% | 31 | 28 |
Other Indications for GEFITINIB
Non-small cell lung cancer (1,786)
Lung neoplasm malignant (779)
Lung adenocarcinoma (556)
Lung adenocarcinoma stage iv (140)
Non-small cell lung cancer metastatic (94)
Product used for unknown indication (85)
Non-small cell lung cancer stage iv (82)
Lung carcinoma cell type unspecified stage 0 (75)
Neoplasm malignant (53)
Adenocarcinoma (43)
Other Drugs Used for Egfr gene mutation
AFATINIB (780)
OSIMERTINIB (695)
AMIVANTAMAB-VMJW (89)
ERLOTINIB (52)
PEMETREXED (34)
CARBOPLATIN (30)
MOBOCERTINIB (26)
BEVACIZUMAB (25)
NINTEDANIB (24)
DOCETAXEL (17)