GLYBURIDE\METFORMIN: 291 Adverse Event Reports & Safety Profile
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291
Total FAERS Reports
24 (8.2%)
Deaths Reported
154
Hospitalizations
291
As Primary/Secondary Suspect
23
Life-Threatening
6
Disabilities
Active Ingredient: GLYBURIDE\METFORMIN HYDROCHLORIDE ·
First Report: 20010811 · Latest Report: 20241028
What Are the Most Common GLYBURIDE\METFORMIN Side Effects?
#1 Most Reported
Hypoglycaemia
104 reports (35.7%)
#2 Most Reported
Acute kidney injury
23 reports (7.9%)
#3 Most Reported
Blood glucose increased
21 reports (7.2%)
All GLYBURIDE\METFORMIN Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Hypoglycaemia | 104 | 35.7% | 7 | 83 |
| Acute kidney injury | 23 | 7.9% | 4 | 17 |
| Asthenia | 21 | 7.2% | 0 | 17 |
| Blood glucose increased | 21 | 7.2% | 0 | 3 |
| Drug ineffective | 20 | 6.9% | 0 | 3 |
| Lactic acidosis | 17 | 5.8% | 3 | 11 |
| Vomiting | 17 | 5.8% | 1 | 12 |
| Malaise | 15 | 5.2% | 0 | 11 |
| Sopor | 14 | 4.8% | 0 | 14 |
| Blood glucose decreased | 12 | 4.1% | 1 | 5 |
| Diarrhoea | 12 | 4.1% | 0 | 2 |
| Medication error | 10 | 3.4% | 0 | 10 |
| Fall | 9 | 3.1% | 4 | 7 |
| Hyperkalaemia | 9 | 3.1% | 1 | 6 |
| Hypertension | 9 | 3.1% | 0 | 4 |
| Nausea | 9 | 3.1% | 0 | 0 |
| Drug abuse | 8 | 2.8% | 0 | 5 |
| Drug interaction | 8 | 2.8% | 0 | 6 |
| Hyperhidrosis | 8 | 2.8% | 0 | 4 |
| Hypoglycaemic coma | 8 | 2.8% | 0 | 7 |
Who Reports GLYBURIDE\METFORMIN Side Effects? Age & Gender Data
Gender: 49.4% female, 50.6% male. Average age: 67.5 years. Most reports from: US. View detailed demographics →
Is GLYBURIDE\METFORMIN Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2001 | 1 | 0 | 0 |
| 2003 | 1 | 0 | 1 |
| 2005 | 2 | 2 | 2 |
| 2007 | 4 | 2 | 0 |
| 2008 | 1 | 0 | 1 |
| 2009 | 3 | 0 | 3 |
| 2010 | 2 | 0 | 0 |
| 2011 | 2 | 0 | 2 |
| 2012 | 15 | 1 | 11 |
| 2013 | 10 | 0 | 7 |
| 2014 | 20 | 5 | 15 |
| 2015 | 24 | 4 | 18 |
| 2016 | 37 | 2 | 24 |
| 2017 | 10 | 0 | 5 |
| 2018 | 20 | 2 | 14 |
| 2019 | 33 | 0 | 25 |
| 2020 | 2 | 0 | 1 |
| 2021 | 2 | 1 | 2 |
| 2022 | 1 | 0 | 0 |
| 2023 | 1 | 0 | 0 |
| 2024 | 3 | 0 | 1 |
What Is GLYBURIDE\METFORMIN Used For?
| Indication | Reports |
|---|---|
| Diabetes mellitus | 100 |
| Type 2 diabetes mellitus | 85 |
| Product used for unknown indication | 67 |
GLYBURIDE\METFORMIN vs Alternatives: Which Is Safer?
GLYBURIDE\METFORMIN vs GLYCERIN
GLYBURIDE\METFORMIN vs GLYCERIN\SORBITOL
GLYBURIDE\METFORMIN vs GLYCEROL PHENYLBUTYRATE
GLYBURIDE\METFORMIN vs GLYCINE\MANNITOL\SODIUM
GLYBURIDE\METFORMIN vs GLYCOPYRROLATE
GLYBURIDE\METFORMIN vs GLYCOPYRROLATE\INDACATEROL
GLYBURIDE\METFORMIN vs GLYCOPYRROLATE\INDACATEROL\MOMETASONE FUROATE
GLYBURIDE\METFORMIN vs GLYCOPYRRONIUM
GLYBURIDE\METFORMIN vs GLYCOPYRRONIUM\INDACATEROL
GLYBURIDE\METFORMIN vs GOLD
Official FDA Label for GLYBURIDE\METFORMIN
Official prescribing information from the FDA-approved drug label.