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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

GUANFACINE vs TIZANIDINE: Which Drug Is Safer?

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GUANFACINE vs TIZANIDINE: Safety Overview

Metric GUANFACINE TIZANIDINE
Total FAERS Reports 3,538 5,533
Deaths Reported 122 1,068
Death Rate 3.4% 19.3%
Hospitalizations 821 1,764
Average Patient Age 17.8 yrs 52.6 yrs
% Female Patients 34.1% 74.0%
FDA Approval Date Apr 15, 2025 Apr 9, 2003
Manufacturer Coupler LLC Preferred Pharmaceuticals Inc.
Route ORAL ORAL
Marketing Status Discontinued Prescription