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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

HISTIDINE: 19 Adverse Event Reports & Safety Profile

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19
Total FAERS Reports
1 (5.3%)
Deaths Reported
16
Hospitalizations
19
As Primary/Secondary Suspect
13
Life-Threatening
Professional Complementary ...
Manufacturer

Route: ORAL · Manufacturer: Professional Complementary Health Formulas · HUMAN OTC DRUG · FDA Label: Available

First Report: 2015 · Latest Report: 20190630

What Are the Most Common HISTIDINE Side Effects?

#1 Most Reported
Vasoplegia syndrome
12 reports (63.2%)
#2 Most Reported
Rhabdomyolysis
12 reports (63.2%)
#3 Most Reported
Pulse absent
12 reports (63.2%)

All HISTIDINE Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Bradycardia 12 63.2% 0 12
Cardiac arrest 12 63.2% 0 12
Cardiogenic shock 12 63.2% 0 12
Coma scale abnormal 12 63.2% 0 12
Compartment syndrome 12 63.2% 0 12
Condition aggravated 12 63.2% 0 12
Hyperkalaemia 12 63.2% 0 12
Hypotension 12 63.2% 0 12
Ileus 12 63.2% 0 12
Lactic acidosis 12 63.2% 0 12
Overdose 12 63.2% 0 12
Pulse absent 12 63.2% 0 12
Rhabdomyolysis 12 63.2% 0 12
Vasoplegia syndrome 12 63.2% 0 12
Off label use 8 42.1% 0 8

Who Reports HISTIDINE Side Effects? Age & Gender Data

Gender: 33.3% female, 66.7% male. Average age: 55.4 years. Most reports from: CA. View detailed demographics →

Is HISTIDINE Getting Safer? Reports by Year

YearReportsDeathsHosp.
2015 1 1 1
2018 2 0 2
2019 1 0 0

View full timeline →

What Is HISTIDINE Used For?

IndicationReports
Overdose 11

Official FDA Label for HISTIDINE

Official prescribing information from the FDA-approved drug label.

FDA Approved Uses (Indications)

INDICATIONS For the temporary relief of minor joint pain or stiffness, indigestion, or symptoms of seasonal or food allergies.*

Dosage & Administration

DIRECTIONS Place drops under tongue 30 minutes before/after meals. Adults and children 12 years and over: Take 10 drops up to 3 times per day. Consult a physician for use in children under 12 years of age.

Warnings

WARNINGS In case of overdose, get medical help or contact a poison control center right away. Keep out of the reach of children. If pregnant or breastfeeding, ask a healthcare professional before use.

Active Ingredient

ACTIVE INGREDIENTS L-Histidine 15X, 20X, 30X, 60X, 200X

Inactive Ingredients

INACTIVE INGREDIENTS 20% ethanol, purified water.