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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

HUMAN IMMUNOGLOBULIN G\HYALURONIDASE: 2,928 Adverse Event Reports & Safety Profile

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2,928
Total FAERS Reports
307 (10.5%)
Deaths Reported
1,227
Hospitalizations
2,928
As Primary/Secondary Suspect
20
Life-Threatening
25
Disabilities

First Report: 20060101 · Latest Report: 20250922

What Are the Most Common HUMAN IMMUNOGLOBULIN G\HYALURONIDASE Side Effects?

#1 Most Reported
Inappropriate schedule of product administration
610 reports (20.8%)
#2 Most Reported
Covid-19
524 reports (17.9%)
#3 Most Reported
Pneumonia
474 reports (16.2%)

All HUMAN IMMUNOGLOBULIN G\HYALURONIDASE Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Inappropriate schedule of product administration 610 20.8% 34 273
Covid-19 524 17.9% 23 246
Pneumonia 474 16.2% 36 308
Sinusitis 453 15.5% 6 192
Fatigue 448 15.3% 16 193
Headache 395 13.5% 9 174
Product dose omission issue 378 12.9% 15 192
Malaise 323 11.0% 16 160
Pyrexia 316 10.8% 23 197
Infusion site erythema 312 10.7% 19 103
Infusion site pain 285 9.7% 9 104
Infection 261 8.9% 13 136
Illness 255 8.7% 9 115
Insurance issue 253 8.6% 3 117
Pain 250 8.5% 6 120
Infusion site swelling 241 8.2% 10 77
Nasopharyngitis 237 8.1% 4 83
Nausea 233 8.0% 5 102
Product use issue 225 7.7% 6 104
Cough 216 7.4% 9 107

Who Reports HUMAN IMMUNOGLOBULIN G\HYALURONIDASE Side Effects? Age & Gender Data

Gender: 65.9% female, 34.1% male. Average age: 51.5 years. Most reports from: US. View detailed demographics →

Is HUMAN IMMUNOGLOBULIN G\HYALURONIDASE Getting Safer? Reports by Year

YearReportsDeathsHosp.
2006 1 0 0
2010 1 0 1
2011 1 0 0
2013 1 0 1
2014 4 0 1
2015 10 0 3
2016 12 0 3
2017 21 1 11
2018 25 0 8
2019 61 4 27
2020 179 12 101
2021 204 17 115
2022 205 17 103
2023 308 48 156
2024 517 78 235
2025 262 34 112

View full timeline →

What Is HUMAN IMMUNOGLOBULIN G\HYALURONIDASE Used For?

IndicationReports
Primary immunodeficiency syndrome 1,170
Immunodeficiency common variable 881
Secondary immunodeficiency 442
Immunodeficiency 404
Product used for unknown indication 267
Hypogammaglobulinaemia 126
Chronic inflammatory demyelinating polyradiculoneuropathy 88
Immune system disorder 51
Plasma cell myeloma 49
Selective igg subclass deficiency 46

HUMAN IMMUNOGLOBULIN G\HYALURONIDASE vs Alternatives: Which Is Safer?

HUMAN IMMUNOGLOBULIN G\HYALURONIDASE vs HUMAN IMMUNOGLOBULIN G\HYALURONIDASE RECOMBINANT HUMAN HUMAN IMMUNOGLOBULIN G\HYALURONIDASE vs HUMAN PAPILLOMAVIRUS QUADRIVALENT VACCINE, RECOMBINANT HUMAN IMMUNOGLOBULIN G\HYALURONIDASE vs HUMAN RABIES VIRUS IMMUNE GLOBULIN HUMAN IMMUNOGLOBULIN G\HYALURONIDASE vs HUMAN RHO IMMUNE GLOBULIN HUMAN IMMUNOGLOBULIN G\HYALURONIDASE vs HUMIRA HUMAN IMMUNOGLOBULIN G\HYALURONIDASE vs HUMIRA PEN HUMAN IMMUNOGLOBULIN G\HYALURONIDASE vs HYALURONATE HUMAN IMMUNOGLOBULIN G\HYALURONIDASE vs HYALURONIC ACID HUMAN IMMUNOGLOBULIN G\HYALURONIDASE vs HYALURONIC ACID\LIDOCAINE HUMAN IMMUNOGLOBULIN G\HYALURONIDASE vs HYALURONIDASE

Official FDA Label for HUMAN IMMUNOGLOBULIN G\HYALURONIDASE

Official prescribing information from the FDA-approved drug label.