HUMIRA: 39,756 Adverse Event Reports & Safety Profile
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39,756
Total FAERS Reports
526 (1.3%)
Deaths Reported
3,568
Hospitalizations
39,756
As Primary/Secondary Suspect
136
Life-Threatening
149
Disabilities
First Report: 1997 · Latest Report: 20141101
What Are the Most Common HUMIRA Side Effects?
#1 Most Reported
Injection site pain
6,005 reports (15.1%)
#2 Most Reported
Drug ineffective
3,506 reports (8.8%)
#3 Most Reported
Arthralgia
2,204 reports (5.5%)
All HUMIRA Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Injection site pain | 6,005 | 15.1% | 0 | 105 |
| Drug ineffective | 3,506 | 8.8% | 11 | 223 |
| Arthralgia | 2,204 | 5.5% | 4 | 215 |
| Pain | 2,045 | 5.1% | 7 | 211 |
| Fatigue | 1,868 | 4.7% | 4 | 126 |
| Psoriasis | 1,857 | 4.7% | 4 | 119 |
| Injection site erythema | 1,654 | 4.2% | 0 | 21 |
| Injection site bruising | 1,623 | 4.1% | 0 | 25 |
| Headache | 1,582 | 4.0% | 7 | 114 |
| Nasopharyngitis | 1,552 | 3.9% | 2 | 55 |
| Nausea | 1,412 | 3.6% | 4 | 179 |
| Incorrect dose administered | 1,377 | 3.5% | 1 | 39 |
| Diarrhoea | 1,374 | 3.5% | 10 | 247 |
| Injection site haemorrhage | 1,304 | 3.3% | 0 | 28 |
| Device malfunction | 1,212 | 3.1% | 0 | 20 |
| Crohn's disease | 1,154 | 2.9% | 10 | 399 |
| Rash | 1,091 | 2.7% | 5 | 54 |
| Injection site pruritus | 1,077 | 2.7% | 0 | 19 |
| Drug dose omission | 1,047 | 2.6% | 1 | 69 |
| Pyrexia | 1,030 | 2.6% | 23 | 290 |
Who Reports HUMIRA Side Effects? Age & Gender Data
Average age: 47.9 years. Most reports from: COUNTRY NOT SPECIFIED. View detailed demographics →
Is HUMIRA Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2000 | 4 | 0 | 1 |
| 2001 | 2 | 0 | 2 |
| 2002 | 5 | 0 | 1 |
| 2003 | 25 | 0 | 3 |
| 2004 | 29 | 0 | 3 |
| 2005 | 41 | 0 | 3 |
| 2006 | 70 | 0 | 12 |
| 2007 | 100 | 3 | 8 |
| 2008 | 156 | 2 | 22 |
| 2009 | 249 | 2 | 47 |
| 2010 | 438 | 12 | 77 |
| 2011 | 802 | 40 | 138 |
| 2012 | 4,011 | 40 | 410 |
| 2013 | 20,981 | 126 | 1,476 |
| 2014 | 1,393 | 130 | 772 |
What Is HUMIRA Used For?
| Indication | Reports |
|---|---|
| Rheumatoid arthritis | 11,051 |
| Crohn's disease | 10,174 |
| Psoriasis | 6,346 |
| Psoriatic arthropathy | 4,070 |
| Product used for unknown indication | 3,953 |
| Colitis ulcerative | 2,707 |
| Ankylosing spondylitis | 1,548 |
| Juvenile idiopathic arthritis | 295 |
| Maternal exposure timing unspecified | 110 |
| Arthritis | 108 |
HUMIRA vs Alternatives: Which Is Safer?
HUMIRA vs HUMIRA PEN
HUMIRA vs HYALURONATE
HUMIRA vs HYALURONIC ACID
HUMIRA vs HYALURONIC ACID\LIDOCAINE
HUMIRA vs HYALURONIDASE
HUMIRA vs HYALURONIDASE-OCSQ\OCRELIZUMAB
HUMIRA vs HYALURONIDASE \RITUXIMAB
HUMIRA vs HYALURONIDASE-ZZXF\PERTUZUMAB\TRASTUZUMAB
HUMIRA vs HYDRALAZINE
HUMIRA vs HYDRALAZINE\ISOSORBIDE DINITRATE
Official FDA Label for HUMIRA
Official prescribing information from the FDA-approved drug label.