HYALURONIDASE \TRASTUZUMAB: 81 Adverse Event Reports & Safety Profile
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81
Total FAERS Reports
11 (13.6%)
Deaths Reported
53
Hospitalizations
81
As Primary/Secondary Suspect
4
Life-Threatening
3
Disabilities
First Report: 20130706 · Latest Report: 20250911
What Are the Most Common HYALURONIDASE \TRASTUZUMAB Side Effects?
#1 Most Reported
Diarrhoea
26 reports (32.1%)
#2 Most Reported
Fatigue
21 reports (25.9%)
#3 Most Reported
Ejection fraction decreased
15 reports (18.5%)
All HYALURONIDASE \TRASTUZUMAB Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 26 | 32.1% | 4 | 23 |
| Fatigue | 21 | 25.9% | 4 | 17 |
| Ejection fraction decreased | 15 | 18.5% | 1 | 12 |
| Alopecia | 13 | 16.1% | 0 | 9 |
| Anaemia | 13 | 16.1% | 0 | 9 |
| Nausea | 13 | 16.1% | 5 | 11 |
| Lymphoedema | 12 | 14.8% | 1 | 9 |
| Pneumonia | 12 | 14.8% | 1 | 12 |
| Vomiting | 12 | 14.8% | 5 | 8 |
| Epistaxis | 10 | 12.4% | 0 | 7 |
| Gastrooesophageal reflux disease | 10 | 12.4% | 1 | 8 |
| Mucosal inflammation | 10 | 12.4% | 1 | 9 |
| Off label use | 10 | 12.4% | 0 | 7 |
| Rash | 10 | 12.4% | 1 | 7 |
| Influenza like illness | 9 | 11.1% | 0 | 7 |
| Pneumothorax | 9 | 11.1% | 1 | 9 |
| Device related infection | 8 | 9.9% | 0 | 7 |
| Headache | 8 | 9.9% | 2 | 4 |
| Hot flush | 8 | 9.9% | 0 | 7 |
| Hypokalaemia | 8 | 9.9% | 1 | 5 |
Who Reports HYALURONIDASE \TRASTUZUMAB Side Effects? Age & Gender Data
Gender: 100.0% female, 0.0% male. Average age: 53.7 years. Most reports from: GB. View detailed demographics →
Is HYALURONIDASE \TRASTUZUMAB Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2013 | 1 | 0 | 1 |
| 2015 | 22 | 5 | 17 |
| 2016 | 5 | 3 | 4 |
| 2017 | 5 | 0 | 4 |
| 2018 | 8 | 2 | 4 |
| 2019 | 11 | 0 | 7 |
| 2020 | 5 | 1 | 5 |
| 2021 | 3 | 0 | 0 |
| 2022 | 15 | 0 | 11 |
| 2025 | 1 | 0 | 0 |
What Is HYALURONIDASE \TRASTUZUMAB Used For?
| Indication | Reports |
|---|---|
| Breast cancer metastatic | 35 |
| Her2 positive breast cancer | 35 |
| Breast cancer | 7 |
Official FDA Label for HYALURONIDASE \TRASTUZUMAB
Official prescribing information from the FDA-approved drug label.