Does HYDROCHLOROTHIAZIDE Cause Acidosis? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Acidosis have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 0.2% of all adverse event reports for HYDROCHLOROTHIAZIDE.
33
Reports of Acidosis with HYDROCHLOROTHIAZIDE
0.2%
of all HYDROCHLOROTHIAZIDE reports
18
Deaths
21
Hospitalizations
How Dangerous Is Acidosis From HYDROCHLOROTHIAZIDE?
Of the 33 reports, 18 (54.5%) resulted in death, 21 (63.6%) required hospitalization, and 17 (51.5%) were considered life-threatening.
Is Acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 33 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Acidosis?
METFORMIN (427)
ACETAMINOPHEN (313)
EMPAGLIFLOZIN (179)
IBUPROFEN (162)
AMLODIPINE (133)
TRAMADOL (116)
TACROLIMUS (114)
MORPHINE (100)
QUETIAPINE (99)
PREDNISONE (94)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Acidosis Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL