Does HYDROCHLOROTHIAZIDE Cause Osteopenia? 34 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 34 reports of Osteopenia have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 0.2% of all adverse event reports for HYDROCHLOROTHIAZIDE.
34
Reports of Osteopenia with HYDROCHLOROTHIAZIDE
0.2%
of all HYDROCHLOROTHIAZIDE reports
11
Deaths
27
Hospitalizations
How Dangerous Is Osteopenia From HYDROCHLOROTHIAZIDE?
Of the 34 reports, 11 (32.4%) resulted in death, 27 (79.4%) required hospitalization, and 9 (26.5%) were considered life-threatening.
Is Osteopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 34 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Osteopenia?
EMTRICITABINE\TENOFOVIR DISOPROXIL (3,892)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,639)
TENOFOVIR DISOPROXIL (2,229)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (1,070)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (886)
METHOTREXATE (591)
ALENDRONATE (590)
ADALIMUMAB (499)
ETANERCEPT (423)
PREDNISONE (382)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Osteopenia Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL