Does HYDROCHLOROTHIAZIDE Cause Presyncope? 257 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 257 reports of Presyncope have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 1.2% of all adverse event reports for HYDROCHLOROTHIAZIDE.
257
Reports of Presyncope with HYDROCHLOROTHIAZIDE
1.2%
of all HYDROCHLOROTHIAZIDE reports
182
Deaths
40
Hospitalizations
How Dangerous Is Presyncope From HYDROCHLOROTHIAZIDE?
Of the 257 reports, 182 (70.8%) resulted in death, 40 (15.6%) required hospitalization, and 7 (2.7%) were considered life-threatening.
Is Presyncope Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 257 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Presyncope?
TREPROSTINIL (585)
BISOPROLOL (485)
LEVONORGESTREL (429)
ADALIMUMAB (420)
AMBRISENTAN (407)
ASPIRIN (370)
TAMSULOSIN (361)
FUROSEMIDE (348)
SERTRALINE (337)
ETANERCEPT (334)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Presyncope Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL