Does HYDROCHLOROTHIAZIDE Cause Rhabdomyolysis? 137 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 137 reports of Rhabdomyolysis have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 0.7% of all adverse event reports for HYDROCHLOROTHIAZIDE.
137
Reports of Rhabdomyolysis with HYDROCHLOROTHIAZIDE
0.7%
of all HYDROCHLOROTHIAZIDE reports
9
Deaths
120
Hospitalizations
How Dangerous Is Rhabdomyolysis From HYDROCHLOROTHIAZIDE?
Of the 137 reports, 9 (6.6%) resulted in death, 120 (87.6%) required hospitalization, and 16 (11.7%) were considered life-threatening.
Is Rhabdomyolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 137 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Rhabdomyolysis?
ATORVASTATIN (3,286)
ROSUVASTATIN (2,173)
SIMVASTATIN (1,616)
LEVETIRACETAM (1,183)
QUETIAPINE (971)
OLANZAPINE (647)
ACETAMINOPHEN (630)
METFORMIN (603)
RISPERIDONE (527)
ARIPIPRAZOLE (516)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Rhabdomyolysis Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL