Does HYDROCHLOROTHIAZIDE Cause Syncope? 675 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 675 reports of Syncope have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 3.2% of all adverse event reports for HYDROCHLOROTHIAZIDE.
675
Reports of Syncope with HYDROCHLOROTHIAZIDE
3.2%
of all HYDROCHLOROTHIAZIDE reports
175
Deaths
357
Hospitalizations
How Dangerous Is Syncope From HYDROCHLOROTHIAZIDE?
Of the 675 reports, 175 (25.9%) resulted in death, 357 (52.9%) required hospitalization, and 33 (4.9%) were considered life-threatening.
Is Syncope Listed in the Official Label?
Yes, Syncope is listed as a known adverse reaction in the official FDA drug label for HYDROCHLOROTHIAZIDE.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Syncope?
AMBRISENTAN (2,140)
TREPROSTINIL (1,908)
ADALIMUMAB (1,795)
FUROSEMIDE (1,431)
LENALIDOMIDE (1,280)
BISOPROLOL (1,279)
METOPROLOL (1,251)
AMLODIPINE (1,224)
ASPIRIN (1,193)
SACUBITRIL\VALSARTAN (1,163)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Syncope Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL