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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

HYDROCHLOROTHIAZIDE\METOPROLOL: 191 Adverse Event Reports & Safety Profile

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191
Total FAERS Reports
32 (16.8%)
Deaths Reported
86
Hospitalizations
191
As Primary/Secondary Suspect
9
Life-Threatening
4
Disabilities

Active Ingredient: HYDROCHLOROTHIAZIDE\METOPROLOL SUCCINATE ·

First Report: 1994 · Latest Report: 20221029

What Are the Most Common HYDROCHLOROTHIAZIDE\METOPROLOL Side Effects?

#1 Most Reported
Dyspnoea
19 reports (9.9%)
#2 Most Reported
Fatigue
16 reports (8.4%)
#3 Most Reported
Drug ineffective
14 reports (7.3%)

All HYDROCHLOROTHIAZIDE\METOPROLOL Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Dyspnoea 19 10.0% 1 18
Fatigue 16 8.4% 0 9
Drug ineffective 14 7.3% 0 7
Hypoaesthesia 13 6.8% 0 13
Muscular weakness 13 6.8% 0 12
Paraesthesia 13 6.8% 0 12
Death 10 5.2% 10 2
Dizziness 10 5.2% 0 4
Blood pressure increased 9 4.7% 2 4
Hypertension 9 4.7% 0 5
Nausea 9 4.7% 2 5
Anaemia 8 4.2% 0 7
Completed suicide 8 4.2% 8 1
Cough 8 4.2% 0 5
Off label use 8 4.2% 1 4
Toxicity to various agents 8 4.2% 7 3
Acute kidney injury 7 3.7% 1 6
Decreased appetite 7 3.7% 0 7
Drug interaction 7 3.7% 2 4
Hypotension 7 3.7% 0 6

Who Reports HYDROCHLOROTHIAZIDE\METOPROLOL Side Effects? Age & Gender Data

Gender: 52.0% female, 48.0% male. Average age: 70.3 years. Most reports from: DE. View detailed demographics →

Is HYDROCHLOROTHIAZIDE\METOPROLOL Getting Safer? Reports by Year

YearReportsDeathsHosp.
2000 1 0 1
2002 1 0 1
2004 4 4 0
2007 1 1 0
2008 2 2 2
2009 5 1 1
2010 1 0 0
2012 1 0 0
2013 5 2 4
2014 5 3 2
2015 10 2 6
2016 12 1 3
2017 8 0 2
2018 2 0 0
2019 6 0 2
2020 1 0 0
2021 2 0 0
2022 11 0 11

View full timeline →

What Is HYDROCHLOROTHIAZIDE\METOPROLOL Used For?

IndicationReports
Product used for unknown indication 75
Hypertension 46

HYDROCHLOROTHIAZIDE\METOPROLOL vs Alternatives: Which Is Safer?

HYDROCHLOROTHIAZIDE\METOPROLOL vs HYDROCHLOROTHIAZIDE\NEBIVOLOL HYDROCHLOROTHIAZIDE\METOPROLOL vs HYDROCHLOROTHIAZIDE\OLMESARTAN MEDOXOMIL HYDROCHLOROTHIAZIDE\METOPROLOL vs HYDROCHLOROTHIAZIDE\QUINAPRIL HYDROCHLOROTHIAZIDE\METOPROLOL vs HYDROCHLOROTHIAZIDE\RAMIPRIL HYDROCHLOROTHIAZIDE\METOPROLOL vs HYDROCHLOROTHIAZIDE\SPIRONOLACTONE HYDROCHLOROTHIAZIDE\METOPROLOL vs HYDROCHLOROTHIAZIDE\TELMISARTAN HYDROCHLOROTHIAZIDE\METOPROLOL vs HYDROCHLOROTHIAZIDE\TRIAMTERENE HYDROCHLOROTHIAZIDE\METOPROLOL vs HYDROCHLOROTHIAZIDE\VALSARTAN HYDROCHLOROTHIAZIDE\METOPROLOL vs HYDROCODONE HYDROCHLOROTHIAZIDE\METOPROLOL vs HYDROCODONE/ACETAMINOPHEN

Official FDA Label for HYDROCHLOROTHIAZIDE\METOPROLOL

Official prescribing information from the FDA-approved drug label.