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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

HYDROCHLOROTHIAZIDE\TRIAMTERENE: 1,164 Adverse Event Reports & Safety Profile

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1,164
Total FAERS Reports
136 (11.7%)
Deaths Reported
333
Hospitalizations
1,164
As Primary/Secondary Suspect
50
Life-Threatening
12
Disabilities

First Report: 19771227 · Latest Report: 20250623

What Are the Most Common HYDROCHLOROTHIAZIDE\TRIAMTERENE Side Effects?

#1 Most Reported
Drug hypersensitivity
154 reports (13.2%)
#2 Most Reported
Drug ineffective
117 reports (10.1%)
#3 Most Reported
Completed suicide
108 reports (9.3%)

All HYDROCHLOROTHIAZIDE\TRIAMTERENE Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Drug hypersensitivity 154 13.2% 0 25
Drug ineffective 117 10.1% 1 5
Completed suicide 108 9.3% 108 31
Dizziness 97 8.3% 0 52
Pruritus 81 7.0% 1 41
Nausea 72 6.2% 0 32
Headache 70 6.0% 0 24
Rash 68 5.8% 0 20
Dyspnoea 65 5.6% 1 35
Hypotension 62 5.3% 0 41
Toxicity to various agents 61 5.2% 46 18
Product substitution issue 59 5.1% 1 17
Asthenia 58 5.0% 0 33
Diarrhoea 58 5.0% 0 28
Fatigue 58 5.0% 0 28
Acute kidney injury 56 4.8% 1 44
Arthralgia 53 4.6% 0 25
Pain 53 4.6% 0 26
Abdominal pain 50 4.3% 0 30
Hyponatraemia 50 4.3% 0 35

Who Reports HYDROCHLOROTHIAZIDE\TRIAMTERENE Side Effects? Age & Gender Data

Gender: 76.4% female, 23.6% male. Average age: 63.6 years. Most reports from: US. View detailed demographics →

Is HYDROCHLOROTHIAZIDE\TRIAMTERENE Getting Safer? Reports by Year

YearReportsDeathsHosp.
2000 3 0 2
2001 1 0 1
2003 2 0 0
2004 1 0 0
2005 4 0 0
2006 3 0 2
2007 4 0 2
2008 7 0 6
2009 3 0 3
2010 19 0 13
2011 21 0 7
2012 6 0 5
2013 13 0 4
2014 31 2 14
2015 50 5 21
2016 57 23 7
2017 70 11 32
2018 35 7 12
2019 27 5 7
2020 30 6 11
2021 25 4 2
2022 26 0 11
2023 7 0 2
2024 6 0 2
2025 2 0 0

View full timeline →

What Is HYDROCHLOROTHIAZIDE\TRIAMTERENE Used For?

IndicationReports
Product used for unknown indication 476
Hypertension 276
Oedema 23
Meniere's disease 22
Blood pressure measurement 21
Diuretic therapy 20
Fluid retention 19
Blood pressure abnormal 17
Peripheral swelling 14
Blood pressure management 12

HYDROCHLOROTHIAZIDE\TRIAMTERENE vs Alternatives: Which Is Safer?

HYDROCHLOROTHIAZIDE\TRIAMTERENE vs HYDROCHLOROTHIAZIDE\VALSARTAN HYDROCHLOROTHIAZIDE\TRIAMTERENE vs HYDROCODONE HYDROCHLOROTHIAZIDE\TRIAMTERENE vs HYDROCODONE/ACETAMINOPHEN HYDROCHLOROTHIAZIDE\TRIAMTERENE vs HYDROCODONE\IBUPROFEN HYDROCHLOROTHIAZIDE\TRIAMTERENE vs HYDROCODONE+PARACETAMOL HYDROCHLOROTHIAZIDE\TRIAMTERENE vs HYDROCORTISONE HYDROCHLOROTHIAZIDE\TRIAMTERENE vs HYDROCORTISONE PROBUTATE HYDROCHLOROTHIAZIDE\TRIAMTERENE vs HYDROCORTISONE\HYDROCORTISONE HYDROCHLOROTHIAZIDE\TRIAMTERENE vs HYDROCORTISONE\NEOMYCIN\POLYMYXIN B HYDROCHLOROTHIAZIDE\TRIAMTERENE vs HYDROCORTISONE\PRAMOXINE

Official FDA Label for HYDROCHLOROTHIAZIDE\TRIAMTERENE

Official prescribing information from the FDA-approved drug label.