HYDROXYUREA for Janus kinase 2 mutation: Side Effects & Safety Data
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There are 5 adverse event reports in the FDA FAERS database where HYDROXYUREA was used for Janus kinase 2 mutation.
Most Reported Side Effects for HYDROXYUREA
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 519 | 8.7% | 63 | 189 |
| Anaemia | 358 | 6.0% | 50 | 188 |
| Drug ineffective | 356 | 6.0% | 81 | 103 |
| Fatigue | 291 | 4.9% | 11 | 94 |
| Thrombocytopenia | 253 | 4.2% | 38 | 149 |
| Nausea | 247 | 4.1% | 8 | 95 |
| Pyrexia | 243 | 4.1% | 37 | 161 |
| Diarrhoea | 222 | 3.7% | 19 | 101 |
| Febrile neutropenia | 202 | 3.4% | 25 | 107 |
| Intentional product use issue | 201 | 3.4% | 11 | 49 |
| Dyspnoea | 184 | 3.1% | 14 | 87 |
| Platelet count decreased | 175 | 2.9% | 27 | 70 |
| Platelet count increased | 174 | 2.9% | 3 | 44 |
| Headache | 173 | 2.9% | 5 | 68 |
| Skin ulcer | 173 | 2.9% | 7 | 60 |
Other Indications for HYDROXYUREA
Product used for unknown indication (1,619)
Essential thrombocythaemia (629)
Polycythaemia vera (552)
Chronic myeloid leukaemia (457)
Sickle cell disease (246)
Acute myeloid leukaemia (230)
Thrombocytosis (184)
Myeloproliferative neoplasm (162)
Myelofibrosis (129)
Sickle cell anaemia (119)