Does IBRUTINIB Cause Aphasia? 111 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 111 reports of Aphasia have been filed in association with IBRUTINIB (Imbruvica). This represents 0.2% of all adverse event reports for IBRUTINIB.
111
Reports of Aphasia with IBRUTINIB
0.2%
of all IBRUTINIB reports
13
Deaths
63
Hospitalizations
How Dangerous Is Aphasia From IBRUTINIB?
Of the 111 reports, 13 (11.7%) resulted in death, 63 (56.8%) required hospitalization, and 14 (12.6%) were considered life-threatening.
Is Aphasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 111 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Aphasia?
METHOTREXATE (509)
ASPIRIN (468)
ADALIMUMAB (461)
DIMETHYL (438)
NATALIZUMAB (433)
METFORMIN (393)
AMLODIPINE (385)
ATORVASTATIN (356)
CARBIDOPA\LEVODOPA (356)
INTERFERON BETA-1A (343)
Which IBRUTINIB Alternatives Have Lower Aphasia Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE