Does IBRUTINIB Cause Atrioventricular block? 45 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 45 reports of Atrioventricular block have been filed in association with IBRUTINIB (Imbruvica). This represents 0.1% of all adverse event reports for IBRUTINIB.
45
Reports of Atrioventricular block with IBRUTINIB
0.1%
of all IBRUTINIB reports
8
Deaths
20
Hospitalizations
How Dangerous Is Atrioventricular block From IBRUTINIB?
Of the 45 reports, 8 (17.8%) resulted in death, 20 (44.4%) required hospitalization, and 3 (6.7%) were considered life-threatening.
Is Atrioventricular block Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 45 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Atrioventricular block?
BISOPROLOL (311)
METOPROLOL (217)
SACUBITRIL\VALSARTAN (181)
FUROSEMIDE (172)
AMIODARONE (154)
AMLODIPINE (140)
LACOSAMIDE (134)
METFORMIN (124)
VERAPAMIL (121)
DIGOXIN (106)
Which IBRUTINIB Alternatives Have Lower Atrioventricular block Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE