Does IBRUTINIB Cause Bradycardia? 106 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 106 reports of Bradycardia have been filed in association with IBRUTINIB (Imbruvica). This represents 0.1% of all adverse event reports for IBRUTINIB.
106
Reports of Bradycardia with IBRUTINIB
0.1%
of all IBRUTINIB reports
9
Deaths
55
Hospitalizations
How Dangerous Is Bradycardia From IBRUTINIB?
Of the 106 reports, 9 (8.5%) resulted in death, 55 (51.9%) required hospitalization, and 1 (0.9%) were considered life-threatening.
Is Bradycardia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 106 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Bradycardia?
BISOPROLOL (2,535)
METOPROLOL (2,024)
AMLODIPINE (1,840)
AMIODARONE (1,261)
FUROSEMIDE (1,032)
ATENOLOL (942)
PROPRANOLOL (934)
DIGOXIN (896)
CARVEDILOL (861)
FINGOLIMOD (861)
Which IBRUTINIB Alternatives Have Lower Bradycardia Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE