Does IBRUTINIB Cause Fracture? 59 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 59 reports of Fracture have been filed in association with IBRUTINIB (Imbruvica). This represents 0.1% of all adverse event reports for IBRUTINIB.
59
Reports of Fracture with IBRUTINIB
0.1%
of all IBRUTINIB reports
4
Deaths
36
Hospitalizations
How Dangerous Is Fracture From IBRUTINIB?
Of the 59 reports, 4 (6.8%) resulted in death, 36 (61.0%) required hospitalization, and 2 (3.4%) were considered life-threatening.
Is Fracture Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 59 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Fracture?
DENOSUMAB (1,392)
EMTRICITABINE\TENOFOVIR DISOPROXIL (1,296)
TENOFOVIR DISOPROXIL (783)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (734)
ROMOSOZUMAB-AQQG (612)
ABATACEPT (543)
TERIPARATIDE (516)
LENALIDOMIDE (463)
ETANERCEPT (384)
METHOTREXATE (319)
Which IBRUTINIB Alternatives Have Lower Fracture Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE