Does IBRUTINIB Cause Hyperkalaemia? 118 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 118 reports of Hyperkalaemia have been filed in association with IBRUTINIB (Imbruvica). This represents 0.2% of all adverse event reports for IBRUTINIB.
118
Reports of Hyperkalaemia with IBRUTINIB
0.2%
of all IBRUTINIB reports
31
Deaths
83
Hospitalizations
How Dangerous Is Hyperkalaemia From IBRUTINIB?
Of the 118 reports, 31 (26.3%) resulted in death, 83 (70.3%) required hospitalization, and 12 (10.2%) were considered life-threatening.
Is Hyperkalaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 118 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Hyperkalaemia?
METFORMIN (2,565)
SPIRONOLACTONE (2,518)
FUROSEMIDE (2,035)
RAMIPRIL (1,383)
SACUBITRIL\VALSARTAN (1,192)
SULFAMETHOXAZOLE\TRIMETHOPRIM (1,036)
LISINOPRIL (948)
POTASSIUM (944)
BISOPROLOL (850)
TACROLIMUS (713)
Which IBRUTINIB Alternatives Have Lower Hyperkalaemia Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE