Does IBRUTINIB Cause Pneumonitis? 262 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 262 reports of Pneumonitis have been filed in association with IBRUTINIB (Imbruvica). This represents 0.4% of all adverse event reports for IBRUTINIB.
262
Reports of Pneumonitis with IBRUTINIB
0.4%
of all IBRUTINIB reports
53
Deaths
140
Hospitalizations
How Dangerous Is Pneumonitis From IBRUTINIB?
Of the 262 reports, 53 (20.2%) resulted in death, 140 (53.4%) required hospitalization, and 18 (6.9%) were considered life-threatening.
Is Pneumonitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 262 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Pneumonitis?
NIVOLUMAB (2,076)
PEMBROLIZUMAB (1,933)
METHOTREXATE (1,188)
PACLITAXEL (1,110)
CARBOPLATIN (975)
EVEROLIMUS (919)
IPILIMUMAB (891)
ATEZOLIZUMAB (842)
DURVALUMAB (827)
RITUXIMAB (747)
Which IBRUTINIB Alternatives Have Lower Pneumonitis Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE