Does IBRUTINIB Cause Rib fracture? 152 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 152 reports of Rib fracture have been filed in association with IBRUTINIB (Imbruvica). This represents 0.2% of all adverse event reports for IBRUTINIB.
152
Reports of Rib fracture with IBRUTINIB
0.2%
of all IBRUTINIB reports
9
Deaths
91
Hospitalizations
How Dangerous Is Rib fracture From IBRUTINIB?
Of the 152 reports, 9 (5.9%) resulted in death, 91 (59.9%) required hospitalization, and 2 (1.3%) were considered life-threatening.
Is Rib fracture Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 152 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Rib fracture?
ADALIMUMAB (739)
LENALIDOMIDE (635)
DENOSUMAB (473)
EMTRICITABINE\TENOFOVIR DISOPROXIL (433)
ALENDRONATE (341)
ETANERCEPT (313)
PREDNISONE (289)
TOFACITINIB (286)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (283)
CARBIDOPA\LEVODOPA (281)
Which IBRUTINIB Alternatives Have Lower Rib fracture Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE