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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

ICATIBANT Drug Interactions: What You Need to Know

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Drug Interactions (FDA Label)

INTERACTIONS

7.1 ACE Inhibitors Icatibant injection is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where Icatibant injection may attenuate the antihypertensive effect of ACE inhibitors. Clinical trials to date have excluded subjects taking ACE inhibitors.

Contraindications

None. None. ( 4 )

Related Warnings

AND PRECAUTIONS Laryngeal attacks: Following treatment of laryngeal attacks with Icatibant injection, advise patients to seek immediate medical attention. ( 5.1 )

5.1 Laryngeal Attacks Given the potential for airway obstruction during acute laryngeal HAE attacks, patients should be advised to seek medical attention in an appropriate healthcare facility immediately in addition to treatment with Icatibant injection.

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