ICOSAPENT: 123 Adverse Event Reports & Safety Profile
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123
Total FAERS Reports
4 (3.3%)
Deaths Reported
87
Hospitalizations
123
As Primary/Secondary Suspect
3
Life-Threatening
1
Disabilities
First Report: 20120822 · Latest Report: 20240826
What Are the Most Common ICOSAPENT Side Effects?
#1 Most Reported
Hepatotoxicity
36 reports (29.3%)
#2 Most Reported
Drug-induced liver injury
35 reports (28.5%)
#3 Most Reported
Hepatic necrosis
33 reports (26.8%)
All ICOSAPENT Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Hepatotoxicity | 36 | 29.3% | 0 | 33 |
| Drug-induced liver injury | 35 | 28.5% | 0 | 34 |
| Hepatic cirrhosis | 33 | 26.8% | 0 | 33 |
| Hepatic encephalopathy | 33 | 26.8% | 0 | 33 |
| Hepatic necrosis | 33 | 26.8% | 0 | 33 |
| Drug interaction | 29 | 23.6% | 0 | 29 |
| Drug ineffective | 24 | 19.5% | 0 | 21 |
| Hypertriglyceridaemia | 16 | 13.0% | 1 | 16 |
| Myocardial infarction | 15 | 12.2% | 0 | 15 |
| Coronary artery disease | 12 | 9.8% | 0 | 12 |
| Acute myocardial infarction | 9 | 7.3% | 0 | 9 |
| Cerebrovascular accident | 9 | 7.3% | 0 | 9 |
| Hypertransaminasaemia | 9 | 7.3% | 1 | 9 |
| Gastrointestinal disorder | 7 | 5.7% | 1 | 7 |
| Increased appetite | 7 | 5.7% | 0 | 6 |
| Cerebral haemorrhage | 5 | 4.1% | 3 | 3 |
Who Reports ICOSAPENT Side Effects? Age & Gender Data
Gender: 50.4% female, 49.6% male. Average age: 50.0 years. Most reports from: CA. View detailed demographics →
Is ICOSAPENT Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2012 | 12 | 0 | 12 |
| 2014 | 8 | 0 | 3 |
| 2015 | 3 | 1 | 2 |
| 2016 | 3 | 0 | 2 |
| 2018 | 4 | 0 | 2 |
| 2019 | 4 | 1 | 3 |
| 2020 | 1 | 0 | 0 |
| 2021 | 3 | 0 | 0 |
| 2024 | 1 | 0 | 1 |
What Is ICOSAPENT Used For?
| Indication | Reports |
|---|---|
| Product used for unknown indication | 65 |
| Hypertriglyceridaemia | 24 |
| Low density lipoprotein | 5 |
ICOSAPENT vs Alternatives: Which Is Safer?
ICOSAPENT vs ICOSAPENT ETHYL
ICOSAPENT vs IDARUBICIN
ICOSAPENT vs IDARUCIZUMAB
ICOSAPENT vs IDECABTAGENE VICLEUCEL
ICOSAPENT vs IDELALISIB
ICOSAPENT vs IDURSULFASE
ICOSAPENT vs IFOSFAMIDE
ICOSAPENT vs IGURATIMOD
ICOSAPENT vs ILOPERIDONE
ICOSAPENT vs ILOPROST
Official FDA Label for ICOSAPENT
Official prescribing information from the FDA-approved drug label.