INTERFERON ALFA-2A: 592 Adverse Event Reports & Safety Profile

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592

Total FAERS Reports

83 (14.0%)

Deaths Reported

171

Hospitalizations

592

As Primary/Secondary Suspect

Life-Threatening

Disabilities

First Report: 19890712 · Latest Report: 20210828

What Are the Most Common INTERFERON ALFA-2A Side Effects?

#1 Most Reported

Fatigue

77 reports (13.0%)

#2 Most Reported

Anaemia

65 reports (11.0%)

#3 Most Reported

Drug ineffective

60 reports (10.1%)

Side Effect	Reports	% of Total	Deaths	Hosp.
Fatigue	77	13.0%	17	15
Anaemia	65	11.0%	10	13
Drug ineffective	60	10.1%	3	17
Nausea	46	7.8%	6	10
Thrombocytopenia	43	7.3%	9	10
Off label use	42	7.1%	7	17
Pyrexia	41	6.9%	6	15
Weight decreased	40	6.8%	10	7
Depression	39	6.6%	9	2
Neutropenia	39	6.6%	7	5
Leukopenia	33	5.6%	2	6
Hepatitis c	32	5.4%	2	3
Headache	27	4.6%	1	7
Vomiting	26	4.4%	6	5
Influenza like illness	24	4.1%	2	2
Rash	23	3.9%	2	5
Alopecia	22	3.7%	0	1
Asthenia	22	3.7%	5	6
Decreased appetite	22	3.7%	4	2
Haemoglobin decreased	22	3.7%	2	14

Gender: 45.5% female, 54.5% male. Average age: 53.7 years. Most reports from: US. View detailed demographics →

Year	Reports	Deaths	Hosp.
2000	6	2	3
2001	6	0	4
2002	7	6	3
2003	10	1	7
2004	5	0	3
2005	3	2	0
2006	1	0	0
2007	4	0	0
2008	9	2	6
2009	11	3	9
2010	19	2	13
2011	22	6	11
2012	26	3	11
2013	21	0	12
2014	26	2	17
2015	21	4	13
2016	8	1	3
2017	5	0	5
2018	2	0	0
2019	12	0	0
2020	2	0	0
2021	1	0	0

Indication	Reports
Hepatitis c	151
Product used for unknown indication	65
Chronic hepatitis c	60
Renal cell carcinoma	48
Metastatic renal cell carcinoma	45
Cutaneous t-cell lymphoma	19
Chronic myeloid leukaemia	16
Hairy cell leukaemia	16
Malignant melanoma	14
B-cell lymphoma	12

Official prescribing information from the FDA-approved drug label.